HBV DNA integration gene CCDC91 is oncogenic and a potential therapeutic target for hepatocellular carcinoma

Abstract Hepatitis B virus (HBV) integration is strongly associated with hepatocellular carcinoma (HCC). However, the genetic alterations and pathogenesis mechanisms remain significantly unexplored, especially for HBV-inserted cancer-related genes. This study identified recurrent HBV DNA integration...

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Bibliographic Details
Main Authors: Mengge Li, Shusheng Wu, Huiqin Luo, Jiayu Niu, Yuan Fang, Wenju Chen, Lulu Cao, Yifu He
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08369-1
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