Identification of energy metabolism and m6A-related gene clusters in Kashin-Beck disease based on bioinformatics analysis

Identification of energy metabolism and m6A-related gene clusters in Kashin-Beck disease based on bioinformatics analysis

Abstract Kashin-Beck disease (KBD) is a chronic and debilitating osteoarthropathy predominantly affecting populations in certain endemic regions. Despite extensive research, the underlying mechanisms of KBD remain poorly understood. Here we analyzed gene expression profiles from KBD patients and hea...

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Bibliographic Details
Main Authors: Ao Zhou, Ji Wang, An Jia, Qi Zhang, Zeren Duoji, Zhengqiang Yu, Zhiyong Huang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Musculoskeletal Disorders
Subjects:
Kashin-Beck disease
Differential gene expression
M6A RNA methylation
Ferroptosis
Energy metabolism
Bioinformatics analysis
Online Access:https://doi.org/10.1186/s12891-025-08922-3
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