Epigenetic modulation elicits an NK cell-mediated immune response in urothelial carcinoma

Epigenetic modulation elicits an NK cell-mediated immune response in urothelial carcinoma

Abstract Urothelial carcinoma (UC), the second most prevalent cancer of the urothelial system, has demonstrated a well-developed ability to evade natural killer (NK) cell-mediated killing via various pathways, highlighting the need for innovative therapeutic approaches. Our study examines the role o...

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Bibliographic Details
Main Authors: Himani Kumari, Ciao-Ni Chen, Hsin-An Shih, Chih-Chieh Yeh, Tsung-Yu Tseng, Hsing-Fen Tsai, Jie Ting Low, Chin Pui Chan, Guan-Ling Lin, Wan-Hong Huang, Chao-Ling Yao, Steven Lin, Cheng-Huang Shen, Michael W. Y. Chan
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Medicine
Subjects:
Urothelial carcinoma
Innate immunity
NKG2DL
ULBP2
CCL3
CPH
Online Access:https://doi.org/10.1186/s10020-025-01264-9
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