Microfluidic Flow Promotes a Steatotic Phenotype in Induced Pluripotent Stem Cell–Derived Hepatocytes that is Influenced by Disease State of the Donor

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Main Authors: Ekta Minocha, Linan Jiang, Ashwani Kumar Gupta, Richard M. Green, Yitshak Zohar, Jason A. Wertheim
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Gastro Hep Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2772572324001973
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author Ekta Minocha
Linan Jiang
Ashwani Kumar Gupta
Richard M. Green
Yitshak Zohar
Jason A. Wertheim
author_facet Ekta Minocha
Linan Jiang
Ashwani Kumar Gupta
Richard M. Green
Yitshak Zohar
Jason A. Wertheim
author_sort Ekta Minocha
collection DOAJ
format Article
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institution Kabale University
issn 2772-5723
language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series Gastro Hep Advances
spelling doaj-art-a7dc867fa1574acfb051fc8456a9215c2025-02-08T05:01:42ZengElsevierGastro Hep Advances2772-57232025-01-0144100601Microfluidic Flow Promotes a Steatotic Phenotype in Induced Pluripotent Stem Cell–Derived Hepatocytes that is Influenced by Disease State of the DonorEkta Minocha0Linan Jiang1Ashwani Kumar Gupta2Richard M. Green3Yitshak Zohar4Jason A. Wertheim5Department of Surgery, University of Arizona College of Medicine, Tucson, Arizona; Surgery Service, Southern Arizona VA Health Care System, Tucson, ArizonaDepartment of Aerospace and Mechanical Engineering, University of Arizona, Tucson, ArizonaDepartment of Surgery, University of Arizona College of Medicine, Tucson, Arizona; Surgery Service, Southern Arizona VA Health Care System, Tucson, ArizonaDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IllinoisDepartment of Aerospace and Mechanical Engineering, University of Arizona, Tucson, Arizona; Yitshak Zohar, PhD, Aerospace and Mechanical Engineering, University of Arizona, Rm. N737, Tucson, Arizona 85721.Department of Surgery, University of Arizona College of Medicine, Tucson, Arizona; Department of Biomedical Engineering, University of Arizona, Tucson, Arizona; Surgery Service, Southern Arizona VA Health Care System, Tucson, Arizona; Correspondence: Address correspondence to: Jason A. Wertheim, MD, PhD, FACS, University of Arizona, College of Medicine, 1501 N. Campbell Ave., P.O. Box 245017, Tucson, Arizona 85724.http://www.sciencedirect.com/science/article/pii/S2772572324001973
spellingShingle Ekta Minocha
Linan Jiang
Ashwani Kumar Gupta
Richard M. Green
Yitshak Zohar
Jason A. Wertheim
Microfluidic Flow Promotes a Steatotic Phenotype in Induced Pluripotent Stem Cell–Derived Hepatocytes that is Influenced by Disease State of the Donor
Gastro Hep Advances
title Microfluidic Flow Promotes a Steatotic Phenotype in Induced Pluripotent Stem Cell–Derived Hepatocytes that is Influenced by Disease State of the Donor
title_full Microfluidic Flow Promotes a Steatotic Phenotype in Induced Pluripotent Stem Cell–Derived Hepatocytes that is Influenced by Disease State of the Donor
title_fullStr Microfluidic Flow Promotes a Steatotic Phenotype in Induced Pluripotent Stem Cell–Derived Hepatocytes that is Influenced by Disease State of the Donor
title_full_unstemmed Microfluidic Flow Promotes a Steatotic Phenotype in Induced Pluripotent Stem Cell–Derived Hepatocytes that is Influenced by Disease State of the Donor
title_short Microfluidic Flow Promotes a Steatotic Phenotype in Induced Pluripotent Stem Cell–Derived Hepatocytes that is Influenced by Disease State of the Donor
title_sort microfluidic flow promotes a steatotic phenotype in induced pluripotent stem cell derived hepatocytes that is influenced by disease state of the donor
url http://www.sciencedirect.com/science/article/pii/S2772572324001973
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