Towards Scalable Electroenzymatic Hydrogen Production with [FeFe]‐Hydrogenase

Abstract The highly efficient [FeFe]‐hydrogenase enzyme could offer a new route to sustainable hydrogen (H2) production in the future, however key issues such as oxygen intolerance, structural fragility upon immobilization, as well as the need to produce the isolated enzyme in scalable quantities re...

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Main Authors: Sophie Webb, Ross D. Milton
Format: Article
Language:English
Published: Wiley-VCH 2025-05-01
Series:ChemElectroChem
Subjects:
Online Access:https://doi.org/10.1002/celc.202400700
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author Sophie Webb
Ross D. Milton
author_facet Sophie Webb
Ross D. Milton
author_sort Sophie Webb
collection DOAJ
description Abstract The highly efficient [FeFe]‐hydrogenase enzyme could offer a new route to sustainable hydrogen (H2) production in the future, however key issues such as oxygen intolerance, structural fragility upon immobilization, as well as the need to produce the isolated enzyme in scalable quantities remains to be solved before this biotechnology becomes viable. This review touches upon some key issues which need to be addressed and provides a perspective on the future of electroenzymatic H2 production by [FeFe]‐hydrogenase.
format Article
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institution Kabale University
issn 2196-0216
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publishDate 2025-05-01
publisher Wiley-VCH
record_format Article
series ChemElectroChem
spelling doaj-art-a7dc6a1867e34864b237d56fb5e9c63a2025-08-20T03:53:57ZengWiley-VCHChemElectroChem2196-02162025-05-011210n/an/a10.1002/celc.202400700Towards Scalable Electroenzymatic Hydrogen Production with [FeFe]‐HydrogenaseSophie Webb0Ross D. Milton1Department of Inorganic and Analytical Chemistry University of Geneva Faculty of Sciences Quai Ernest-Ansermet 30 1211 Geneva 4 SwitzerlandDepartment of Inorganic and Analytical Chemistry University of Geneva Faculty of Sciences Quai Ernest-Ansermet 30 1211 Geneva 4 SwitzerlandAbstract The highly efficient [FeFe]‐hydrogenase enzyme could offer a new route to sustainable hydrogen (H2) production in the future, however key issues such as oxygen intolerance, structural fragility upon immobilization, as well as the need to produce the isolated enzyme in scalable quantities remains to be solved before this biotechnology becomes viable. This review touches upon some key issues which need to be addressed and provides a perspective on the future of electroenzymatic H2 production by [FeFe]‐hydrogenase.https://doi.org/10.1002/celc.202400700[FeFe]-hydrogenaseElectrocatalysisHydrogenBio-electrocatalysisBioelectrode
spellingShingle Sophie Webb
Ross D. Milton
Towards Scalable Electroenzymatic Hydrogen Production with [FeFe]‐Hydrogenase
ChemElectroChem
[FeFe]-hydrogenase
Electrocatalysis
Hydrogen
Bio-electrocatalysis
Bioelectrode
title Towards Scalable Electroenzymatic Hydrogen Production with [FeFe]‐Hydrogenase
title_full Towards Scalable Electroenzymatic Hydrogen Production with [FeFe]‐Hydrogenase
title_fullStr Towards Scalable Electroenzymatic Hydrogen Production with [FeFe]‐Hydrogenase
title_full_unstemmed Towards Scalable Electroenzymatic Hydrogen Production with [FeFe]‐Hydrogenase
title_short Towards Scalable Electroenzymatic Hydrogen Production with [FeFe]‐Hydrogenase
title_sort towards scalable electroenzymatic hydrogen production with fefe hydrogenase
topic [FeFe]-hydrogenase
Electrocatalysis
Hydrogen
Bio-electrocatalysis
Bioelectrode
url https://doi.org/10.1002/celc.202400700
work_keys_str_mv AT sophiewebb towardsscalableelectroenzymatichydrogenproductionwithfefehydrogenase
AT rossdmilton towardsscalableelectroenzymatichydrogenproductionwithfefehydrogenase