Comparative analysis of replication and immune evasion among SARS-CoV-2 subvariants BA.2.86, JN.1, KP.2, and KP.3

Comparative analysis of replication and immune evasion among SARS-CoV-2 subvariants BA.2.86, JN.1, KP.2, and KP.3

ABSTRACT The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BA.2.86 sublineage and its descendants (JN.1, KP.2, and KP.3) have acquired key recurrent mutations (R346T, L455S, F456L, and Q493E) and became predominant strains, following the epidemiological progression: BA.2.86→JN.1→KP.2→...

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Bibliographic Details
Main Authors: Yanping Hu, Jing Zou, Michael D. Nguyen, Hope C. Chang, Jason Yeung, Haiping Hao, Pei-Yong Shi, Ping Ren, Xuping Xie
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:mBio
Subjects:
SARS-CoV-2
immune evasion
BA.2.86
JN.1
KP.2
KP.3
Online Access:https://journals.asm.org/doi/10.1128/mbio.03503-24
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