Release Rates of Prednisolone-21-Hydrogen- Succinate from 3D-Printed Silicone as Material for Patient-Individualized Drug Releasing Implants

Release Rates of Prednisolone-21-Hydrogen- Succinate from 3D-Printed Silicone as Material for Patient-Individualized Drug Releasing Implants

For treating idiopathic sudden sensorineural hearing loss, prednisolone is commonly used. However, systemic or middle ear injections often lead to insufficient drug delivery to the inner ear, causing ineffective treatment and systemic side effects. An implant inserted into the middle ear and deliver...

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Bibliographic Details
Main Authors: Knabel Martina, Dräger Gerald, Lenarz Thomas, Scheper Verena
Format: Article
Language:English
Published: De Gruyter 2024-12-01
Series:Current Directions in Biomedical Engineering
Subjects:
3d printing
release kinetics
release rates
inner ear therapy
individualized implant
prednisolone
silicone
drug delivery
Online Access:https://doi.org/10.1515/cdbme-2024-2091
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