Setup Error and Its Influencing Factors in Radiotherapy for Spinal Metastasis

ObjectiveTo investigate the setup error in patients with spinal bone metastasis who underwent radiotherapy under the guidance of kilovoltage cone-beam CT (KV-CBCT). MethodsA total of 118 patients with spinal metastasis who underwent radiotherapy, including 17 cases of cervical spine, 62 cases of tho...

Full description

Saved in:
Bibliographic Details
Main Authors: Wenhua QIN, Xin FENG, Zengzhou WANG, Shangnan CHU, Hong WANG, Shiyu WU, Cheng CHEN, Fukui HUAN, Bin LIANG, Tao ZHANG
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2025-05-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1084
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849689552733601792
author Wenhua QIN
Xin FENG
Zengzhou WANG
Shangnan CHU
Hong WANG
Shiyu WU
Cheng CHEN
Fukui HUAN
Bin LIANG
Tao ZHANG
author_facet Wenhua QIN
Xin FENG
Zengzhou WANG
Shangnan CHU
Hong WANG
Shiyu WU
Cheng CHEN
Fukui HUAN
Bin LIANG
Tao ZHANG
author_sort Wenhua QIN
collection DOAJ
description ObjectiveTo investigate the setup error in patients with spinal bone metastasis who underwent radiotherapy under the guidance of kilovoltage cone-beam CT (KV-CBCT). MethodsA total of 118 patients with spinal metastasis who underwent radiotherapy, including 17 cases of cervical spine, 62 cases of thoracic spine, and 39 cases of lumbar spine, were collected. KV-CBCT scans were performed using the linear accelerators from Elekta and Varian’s EDGE system. CBCT images were registered with reference CT images in the bone window mode. A total of 973 data were collected, and 3D linear errors were recorded. ResultsThe patients with spinal bone metastasis were grouped by site, height, weight, and BMI. The P value of the patients grouped only by site was P<0.05, which was statistically significant. ConclusionWhen grouped by site in the 3D direction, the positioning effect of cervical spine is better than that of thoracic and lumbar spine. The positioning effect of the thoracic spine is better in the head and foot direction but worse in the left and right direction compared with that of the lumbar spine. Instead of extending or narrowing the margin according to the BMI of patients with spinal metastasis, the margin must be changed according to the site of spinal bone metastasis.
format Article
id doaj-art-a7bea095bbbf4800bd1884e10ea245c6
institution DOAJ
issn 1000-8578
language zho
publishDate 2025-05-01
publisher Magazine House of Cancer Research on Prevention and Treatment
record_format Article
series Zhongliu Fangzhi Yanjiu
spelling doaj-art-a7bea095bbbf4800bd1884e10ea245c62025-08-20T03:21:34ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85782025-05-0152540040410.3971/j.issn.1000-8578.2025.24.108420241084Setup Error and Its Influencing Factors in Radiotherapy for Spinal MetastasisWenhua QIN0Xin FENG1Zengzhou WANG2Shangnan CHU3Hong WANG4Shiyu WU5Cheng CHEN6Fukui HUAN7Bin LIANG8Tao ZHANG9Department of Radiotherapy, National Cancer Center/National Clinical Research Center For Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, ChinaDepartment of Radiotherapy, National Cancer Center/National Clinical Research Center For Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, ChinaDepartment of Radiotherapy, National Cancer Center/National Clinical Research Center For Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, ChinaDepartment of Radiotherapy, Peking University Cancer Hospital and Beijing Institute of Cancer Prevention and Treatment, Key Laboratory of Pathogenesis and Transformation of Malignant Tumor, Ministry of Education, Beijing 100142, ChinaDepartment of Radiotherapy, National Cancer Center/National Clinical Research Center For Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, ChinaDepartment of Radiotherapy, National Cancer Center/National Clinical Research Center For Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, ChinaDepartment of Radiotherapy, National Cancer Center/National Clinical Research Center For Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, ChinaDepartment of Radiotherapy, National Cancer Center/National Clinical Research Center For Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, ChinaDepartment of Radiotherapy, National Cancer Center/National Clinical Research Center For Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, ChinaDepartment of Radiotherapy, National Cancer Center/National Clinical Research Center For Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, ChinaObjectiveTo investigate the setup error in patients with spinal bone metastasis who underwent radiotherapy under the guidance of kilovoltage cone-beam CT (KV-CBCT). MethodsA total of 118 patients with spinal metastasis who underwent radiotherapy, including 17 cases of cervical spine, 62 cases of thoracic spine, and 39 cases of lumbar spine, were collected. KV-CBCT scans were performed using the linear accelerators from Elekta and Varian’s EDGE system. CBCT images were registered with reference CT images in the bone window mode. A total of 973 data were collected, and 3D linear errors were recorded. ResultsThe patients with spinal bone metastasis were grouped by site, height, weight, and BMI. The P value of the patients grouped only by site was P<0.05, which was statistically significant. ConclusionWhen grouped by site in the 3D direction, the positioning effect of cervical spine is better than that of thoracic and lumbar spine. The positioning effect of the thoracic spine is better in the head and foot direction but worse in the left and right direction compared with that of the lumbar spine. Instead of extending or narrowing the margin according to the BMI of patients with spinal metastasis, the margin must be changed according to the site of spinal bone metastasis.http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1084cone beam ctspinal bone metastasisradiotherapysetup errorinfluencing factorsbmi
spellingShingle Wenhua QIN
Xin FENG
Zengzhou WANG
Shangnan CHU
Hong WANG
Shiyu WU
Cheng CHEN
Fukui HUAN
Bin LIANG
Tao ZHANG
Setup Error and Its Influencing Factors in Radiotherapy for Spinal Metastasis
Zhongliu Fangzhi Yanjiu
cone beam ct
spinal bone metastasis
radiotherapy
setup error
influencing factors
bmi
title Setup Error and Its Influencing Factors in Radiotherapy for Spinal Metastasis
title_full Setup Error and Its Influencing Factors in Radiotherapy for Spinal Metastasis
title_fullStr Setup Error and Its Influencing Factors in Radiotherapy for Spinal Metastasis
title_full_unstemmed Setup Error and Its Influencing Factors in Radiotherapy for Spinal Metastasis
title_short Setup Error and Its Influencing Factors in Radiotherapy for Spinal Metastasis
title_sort setup error and its influencing factors in radiotherapy for spinal metastasis
topic cone beam ct
spinal bone metastasis
radiotherapy
setup error
influencing factors
bmi
url http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1084
work_keys_str_mv AT wenhuaqin setuperroranditsinfluencingfactorsinradiotherapyforspinalmetastasis
AT xinfeng setuperroranditsinfluencingfactorsinradiotherapyforspinalmetastasis
AT zengzhouwang setuperroranditsinfluencingfactorsinradiotherapyforspinalmetastasis
AT shangnanchu setuperroranditsinfluencingfactorsinradiotherapyforspinalmetastasis
AT hongwang setuperroranditsinfluencingfactorsinradiotherapyforspinalmetastasis
AT shiyuwu setuperroranditsinfluencingfactorsinradiotherapyforspinalmetastasis
AT chengchen setuperroranditsinfluencingfactorsinradiotherapyforspinalmetastasis
AT fukuihuan setuperroranditsinfluencingfactorsinradiotherapyforspinalmetastasis
AT binliang setuperroranditsinfluencingfactorsinradiotherapyforspinalmetastasis
AT taozhang setuperroranditsinfluencingfactorsinradiotherapyforspinalmetastasis