Optimizing miRNA-module diagnostic biomarkers of gastric carcinoma via integrated network analysis.

Optimizing miRNA-module diagnostic biomarkers of gastric carcinoma via integrated network analysis.

Several microRNAs (miRNAs) have been suggested as novel biomarkers for diagnosing gastric cancer (GC) at an early stage, but the single-marker strategy may ignore the co-regulatory relationships and lead to low diagnostic specificity. Thus, multi-target modular diagnostic biomarkers are urgently nee...

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Bibliographic Details
Main Authors: Fengbin Zhang, Wenjuan Xu, Jun Liu, Xiaoyan Liu, Bingjie Huo, Bing Li, Zhong Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198445/1/pone.0198445.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210222%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210222T180618Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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