Non-resolving pneumonia as a clinical clue to paediatric neuroendocrine tumour: A case report
An 8-year-old girl presented with persistent fever and cough unresponsive to antibiotics, initially diagnosed as pneumonia. Imaging revealed a right upper lobe mass with collapse-consolidation. Bronchoscopy identified multiple endobronchial lesions; biopsy confirmed a World Health Organization (WHO)...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | The Journal of Association of Chest Physicians |
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| Online Access: | https://journals.lww.com/10.4103/jacp.jacp_44_24 |
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| author | Praveen Valsalan Aparna S. Nirmal Sowmya Kongara Sharon Anne Thomas Vineetha K. Tisa Paul |
| author_facet | Praveen Valsalan Aparna S. Nirmal Sowmya Kongara Sharon Anne Thomas Vineetha K. Tisa Paul |
| author_sort | Praveen Valsalan |
| collection | DOAJ |
| description | An 8-year-old girl presented with persistent fever and cough unresponsive to antibiotics, initially diagnosed as pneumonia. Imaging revealed a right upper lobe mass with collapse-consolidation. Bronchoscopy identified multiple endobronchial lesions; biopsy confirmed a World Health Organization (WHO) grade 2 neuroendocrine tumour. Positron emission tomography (PET)-CT with Gallium-68 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-1-NaI3-octreotide (a radiotracer for somatostatin receptor imaging)(DOTANOC) showed localized disease. The patient underwent right upper lobectomy and recovered uneventfully, with radiological improvement at follow-up. This case highlights the diagnostic challenge of paediatric bronchial neuroendocrine tumours, which often mimic common respiratory infections and lead to delayed diagnosis. Early clinical suspicion, appropriate imaging, and multidisciplinary management are essential for optimal outcomes. Complete surgical resection offers good prognosis in localized disease, but long-term follow-up is necessary due to the risk of late recurrence. |
| format | Article |
| id | doaj-art-a7946308c1dd47bcb1005755ef70e505 |
| institution | OA Journals |
| issn | 2320-8775 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Journal of Association of Chest Physicians |
| spelling | doaj-art-a7946308c1dd47bcb1005755ef70e5052025-08-20T02:16:21ZengWolters Kluwer Medknow PublicationsThe Journal of Association of Chest Physicians2320-87752025-01-01131202310.4103/jacp.jacp_44_24Non-resolving pneumonia as a clinical clue to paediatric neuroendocrine tumour: A case reportPraveen ValsalanAparna S. NirmalSowmya KongaraSharon Anne ThomasVineetha K.Tisa PaulAn 8-year-old girl presented with persistent fever and cough unresponsive to antibiotics, initially diagnosed as pneumonia. Imaging revealed a right upper lobe mass with collapse-consolidation. Bronchoscopy identified multiple endobronchial lesions; biopsy confirmed a World Health Organization (WHO) grade 2 neuroendocrine tumour. Positron emission tomography (PET)-CT with Gallium-68 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-1-NaI3-octreotide (a radiotracer for somatostatin receptor imaging)(DOTANOC) showed localized disease. The patient underwent right upper lobectomy and recovered uneventfully, with radiological improvement at follow-up. This case highlights the diagnostic challenge of paediatric bronchial neuroendocrine tumours, which often mimic common respiratory infections and lead to delayed diagnosis. Early clinical suspicion, appropriate imaging, and multidisciplinary management are essential for optimal outcomes. Complete surgical resection offers good prognosis in localized disease, but long-term follow-up is necessary due to the risk of late recurrence.https://journals.lww.com/10.4103/jacp.jacp_44_24paediatric neuroendocrine tumourbronchial carcinoidnon-resolving pneumoniaendobronchial masssurgical resectiongallium-68 dotanoc pet-ctcase report |
| spellingShingle | Praveen Valsalan Aparna S. Nirmal Sowmya Kongara Sharon Anne Thomas Vineetha K. Tisa Paul Non-resolving pneumonia as a clinical clue to paediatric neuroendocrine tumour: A case report The Journal of Association of Chest Physicians paediatric neuroendocrine tumour bronchial carcinoid non-resolving pneumonia endobronchial mass surgical resection gallium-68 dotanoc pet-ct case report |
| title | Non-resolving pneumonia as a clinical clue to paediatric neuroendocrine tumour: A case report |
| title_full | Non-resolving pneumonia as a clinical clue to paediatric neuroendocrine tumour: A case report |
| title_fullStr | Non-resolving pneumonia as a clinical clue to paediatric neuroendocrine tumour: A case report |
| title_full_unstemmed | Non-resolving pneumonia as a clinical clue to paediatric neuroendocrine tumour: A case report |
| title_short | Non-resolving pneumonia as a clinical clue to paediatric neuroendocrine tumour: A case report |
| title_sort | non resolving pneumonia as a clinical clue to paediatric neuroendocrine tumour a case report |
| topic | paediatric neuroendocrine tumour bronchial carcinoid non-resolving pneumonia endobronchial mass surgical resection gallium-68 dotanoc pet-ct case report |
| url | https://journals.lww.com/10.4103/jacp.jacp_44_24 |
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