Exploration of the varieties differences on the volatile and non-volatile metabolites of Alpinia galanga and Myristica fragrans utilizing electronic sensing evaluation and untargeted metabolomics analysis

There are differences in flavor, efficacy, and price between the cardamom varieties Alpinia galanga (H) and Myristica fragrans (R). It is crucial to distinguish their bioactivities and metabolites, given their high economic value and dietary frequency. This study determined total phenolic content (T...

Full description

Saved in:
Bibliographic Details
Main Authors: Haijiao Lin, Xiangmin Li, Zengyi Song, Yu Liu, Zijia Li, Qingyun He, Binbin Wei, Ziwen Wang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Food Chemistry: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S259015752500361X
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849725488139862016
author Haijiao Lin
Xiangmin Li
Zengyi Song
Yu Liu
Zijia Li
Qingyun He
Binbin Wei
Ziwen Wang
author_facet Haijiao Lin
Xiangmin Li
Zengyi Song
Yu Liu
Zijia Li
Qingyun He
Binbin Wei
Ziwen Wang
author_sort Haijiao Lin
collection DOAJ
description There are differences in flavor, efficacy, and price between the cardamom varieties Alpinia galanga (H) and Myristica fragrans (R). It is crucial to distinguish their bioactivities and metabolites, given their high economic value and dietary frequency. This study determined total phenolic content (TPC), total flavonoid content (TFC), and in vitro/cellular antioxidant activities of R and H. Their volatile/non-volatile metabolites were analyzed via electronic sensing (E-nose, HS-GC–MS/MS) and untargeted metabolomics (UPLC-ESI-QTOF/MSE). Results demonstrated that R exhibited superior antioxidant capacity to H, with both correlating positively with TPC and TFC. A total of 195 non-volatile metabolites were identified and Malabaricone C, alkyl-DHAP, and (R)-Shinanolone were the key components for distinguishing them. E-nose showed W1C, W2W and W5S sensors were more sensitive. Furthermore, 219 kinds of volatile metabolites were identified, among which 14 key differential volatile components were screened out. The study established a theoretical basis for differentiating and characterizing both cardamoms.
format Article
id doaj-art-a78b428c7fbb4f8984d69c47d0d0f332
institution DOAJ
issn 2590-1575
language English
publishDate 2025-05-01
publisher Elsevier
record_format Article
series Food Chemistry: X
spelling doaj-art-a78b428c7fbb4f8984d69c47d0d0f3322025-08-20T03:10:27ZengElsevierFood Chemistry: X2590-15752025-05-012810251410.1016/j.fochx.2025.102514Exploration of the varieties differences on the volatile and non-volatile metabolites of Alpinia galanga and Myristica fragrans utilizing electronic sensing evaluation and untargeted metabolomics analysisHaijiao Lin0Xiangmin Li1Zengyi Song2Yu Liu3Zijia Li4Qingyun He5Binbin Wei6Ziwen Wang7School of Pharmacy, China Medical University, No.77 Puhe Road, Shenyang 110122, PR ChinaDepartment of Oncology, Shengjing Hospital of China Medical University, No.36 Sanhao Street, Heping District, Shenyang 110004, PR ChinaSchool of Pharmacy, China Medical University, No.77 Puhe Road, Shenyang 110122, PR ChinaSchool of Pharmacy, China Medical University, No.77 Puhe Road, Shenyang 110122, PR ChinaSchool of Pharmacy, China Medical University, No.77 Puhe Road, Shenyang 110122, PR ChinaSchool of Pharmacy, China Medical University, No.77 Puhe Road, Shenyang 110122, PR ChinaSchool of Pharmacy, China Medical University, No.77 Puhe Road, Shenyang 110122, PR China; Corresponding authors.Department of Radiology, Shengjing Hospital of China Medical University, No.36 Sanhao Street, Heping District, Shenyang 110001, PR China; Corresponding authors.There are differences in flavor, efficacy, and price between the cardamom varieties Alpinia galanga (H) and Myristica fragrans (R). It is crucial to distinguish their bioactivities and metabolites, given their high economic value and dietary frequency. This study determined total phenolic content (TPC), total flavonoid content (TFC), and in vitro/cellular antioxidant activities of R and H. Their volatile/non-volatile metabolites were analyzed via electronic sensing (E-nose, HS-GC–MS/MS) and untargeted metabolomics (UPLC-ESI-QTOF/MSE). Results demonstrated that R exhibited superior antioxidant capacity to H, with both correlating positively with TPC and TFC. A total of 195 non-volatile metabolites were identified and Malabaricone C, alkyl-DHAP, and (R)-Shinanolone were the key components for distinguishing them. E-nose showed W1C, W2W and W5S sensors were more sensitive. Furthermore, 219 kinds of volatile metabolites were identified, among which 14 key differential volatile components were screened out. The study established a theoretical basis for differentiating and characterizing both cardamoms.http://www.sciencedirect.com/science/article/pii/S259015752500361XUntargeted metabolomicsAntioxidant activityHS-GC–MS/MSE-noseCardamom
spellingShingle Haijiao Lin
Xiangmin Li
Zengyi Song
Yu Liu
Zijia Li
Qingyun He
Binbin Wei
Ziwen Wang
Exploration of the varieties differences on the volatile and non-volatile metabolites of Alpinia galanga and Myristica fragrans utilizing electronic sensing evaluation and untargeted metabolomics analysis
Food Chemistry: X
Untargeted metabolomics
Antioxidant activity
HS-GC–MS/MS
E-nose
Cardamom
title Exploration of the varieties differences on the volatile and non-volatile metabolites of Alpinia galanga and Myristica fragrans utilizing electronic sensing evaluation and untargeted metabolomics analysis
title_full Exploration of the varieties differences on the volatile and non-volatile metabolites of Alpinia galanga and Myristica fragrans utilizing electronic sensing evaluation and untargeted metabolomics analysis
title_fullStr Exploration of the varieties differences on the volatile and non-volatile metabolites of Alpinia galanga and Myristica fragrans utilizing electronic sensing evaluation and untargeted metabolomics analysis
title_full_unstemmed Exploration of the varieties differences on the volatile and non-volatile metabolites of Alpinia galanga and Myristica fragrans utilizing electronic sensing evaluation and untargeted metabolomics analysis
title_short Exploration of the varieties differences on the volatile and non-volatile metabolites of Alpinia galanga and Myristica fragrans utilizing electronic sensing evaluation and untargeted metabolomics analysis
title_sort exploration of the varieties differences on the volatile and non volatile metabolites of alpinia galanga and myristica fragrans utilizing electronic sensing evaluation and untargeted metabolomics analysis
topic Untargeted metabolomics
Antioxidant activity
HS-GC–MS/MS
E-nose
Cardamom
url http://www.sciencedirect.com/science/article/pii/S259015752500361X
work_keys_str_mv AT haijiaolin explorationofthevarietiesdifferencesonthevolatileandnonvolatilemetabolitesofalpiniagalangaandmyristicafragransutilizingelectronicsensingevaluationanduntargetedmetabolomicsanalysis
AT xiangminli explorationofthevarietiesdifferencesonthevolatileandnonvolatilemetabolitesofalpiniagalangaandmyristicafragransutilizingelectronicsensingevaluationanduntargetedmetabolomicsanalysis
AT zengyisong explorationofthevarietiesdifferencesonthevolatileandnonvolatilemetabolitesofalpiniagalangaandmyristicafragransutilizingelectronicsensingevaluationanduntargetedmetabolomicsanalysis
AT yuliu explorationofthevarietiesdifferencesonthevolatileandnonvolatilemetabolitesofalpiniagalangaandmyristicafragransutilizingelectronicsensingevaluationanduntargetedmetabolomicsanalysis
AT zijiali explorationofthevarietiesdifferencesonthevolatileandnonvolatilemetabolitesofalpiniagalangaandmyristicafragransutilizingelectronicsensingevaluationanduntargetedmetabolomicsanalysis
AT qingyunhe explorationofthevarietiesdifferencesonthevolatileandnonvolatilemetabolitesofalpiniagalangaandmyristicafragransutilizingelectronicsensingevaluationanduntargetedmetabolomicsanalysis
AT binbinwei explorationofthevarietiesdifferencesonthevolatileandnonvolatilemetabolitesofalpiniagalangaandmyristicafragransutilizingelectronicsensingevaluationanduntargetedmetabolomicsanalysis
AT ziwenwang explorationofthevarietiesdifferencesonthevolatileandnonvolatilemetabolitesofalpiniagalangaandmyristicafragransutilizingelectronicsensingevaluationanduntargetedmetabolomicsanalysis