Dabie bandavirus and Mycoplasma pneumoniae co-infection: a case report
Abstract Background Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by Dabie bandavirus (DBV). We report a case of DBV and Mycoplasma pneumoniae (MP) co-infection. Case presentation Here we reported a 57-year-old healthy male who was admitted with the pres...
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| Format: | Article |
| Language: | English |
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BMC
2025-01-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | https://doi.org/10.1186/s12879-024-10392-2 |
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| author | Yasi Tu Miao Deng Xueying Zhang Tianxin Xiang Daxian Wu |
| author_facet | Yasi Tu Miao Deng Xueying Zhang Tianxin Xiang Daxian Wu |
| author_sort | Yasi Tu |
| collection | DOAJ |
| description | Abstract Background Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by Dabie bandavirus (DBV). We report a case of DBV and Mycoplasma pneumoniae (MP) co-infection. Case presentation Here we reported a 57-year-old healthy male who was admitted with the presentations of fever, cough, hemoptysis, and hypotension. Laboratory investigations revealed thrombocytopenia, leukopenia, and organ dysfunction of liver and kidney. Seroconversion from Mycoplasma IgM antibody to IgG was recorded, and SFTS was confirmed through metagenomic next-generation sequencing. In addition, hemophagocytic lymphohistiocytosis was diagnosed in the context of DBV and MP coinfection. The patient exhibited a rapid recovery following treatment with omadacycline and essential symptomatic and supportive treatment. Conclusions We firstly reported a case with DBV and MP coinfection, which reminded us that the symptoms of DBV infection were bewildering and easy to miss diagnosis when it was co-infection with other etiologies. |
| format | Article |
| id | doaj-art-a77ed41ced3a4ad890bf421ede6159e0 |
| institution | DOAJ |
| issn | 1471-2334 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj-art-a77ed41ced3a4ad890bf421ede6159e02025-08-20T02:40:32ZengBMCBMC Infectious Diseases1471-23342025-01-012511610.1186/s12879-024-10392-2Dabie bandavirus and Mycoplasma pneumoniae co-infection: a case reportYasi Tu0Miao Deng1Xueying Zhang2Tianxin Xiang3Daxian Wu4Jiangxi Medical Center for Critical Public Health Events, Department of Infectious Diseases, The First Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityJiangxi Medical Center for Critical Public Health Events, Department of Infectious Diseases, The First Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityJiangxi Medical Center for Critical Public Health Events, Department of Infectious Diseases, The First Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityJiangxi Medical Center for Critical Public Health Events, Department of Infectious Diseases, The First Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityJiangxi Medical Center for Critical Public Health Events, Department of Infectious Diseases, The First Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityAbstract Background Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by Dabie bandavirus (DBV). We report a case of DBV and Mycoplasma pneumoniae (MP) co-infection. Case presentation Here we reported a 57-year-old healthy male who was admitted with the presentations of fever, cough, hemoptysis, and hypotension. Laboratory investigations revealed thrombocytopenia, leukopenia, and organ dysfunction of liver and kidney. Seroconversion from Mycoplasma IgM antibody to IgG was recorded, and SFTS was confirmed through metagenomic next-generation sequencing. In addition, hemophagocytic lymphohistiocytosis was diagnosed in the context of DBV and MP coinfection. The patient exhibited a rapid recovery following treatment with omadacycline and essential symptomatic and supportive treatment. Conclusions We firstly reported a case with DBV and MP coinfection, which reminded us that the symptoms of DBV infection were bewildering and easy to miss diagnosis when it was co-infection with other etiologies.https://doi.org/10.1186/s12879-024-10392-2CoinfectionDabie BandavirusHemophagocytic lymphohistiocytosisMetagenomic next-generation sequencingMycoplasma pneumoniae |
| spellingShingle | Yasi Tu Miao Deng Xueying Zhang Tianxin Xiang Daxian Wu Dabie bandavirus and Mycoplasma pneumoniae co-infection: a case report BMC Infectious Diseases Coinfection Dabie Bandavirus Hemophagocytic lymphohistiocytosis Metagenomic next-generation sequencing Mycoplasma pneumoniae |
| title | Dabie bandavirus and Mycoplasma pneumoniae co-infection: a case report |
| title_full | Dabie bandavirus and Mycoplasma pneumoniae co-infection: a case report |
| title_fullStr | Dabie bandavirus and Mycoplasma pneumoniae co-infection: a case report |
| title_full_unstemmed | Dabie bandavirus and Mycoplasma pneumoniae co-infection: a case report |
| title_short | Dabie bandavirus and Mycoplasma pneumoniae co-infection: a case report |
| title_sort | dabie bandavirus and mycoplasma pneumoniae co infection a case report |
| topic | Coinfection Dabie Bandavirus Hemophagocytic lymphohistiocytosis Metagenomic next-generation sequencing Mycoplasma pneumoniae |
| url | https://doi.org/10.1186/s12879-024-10392-2 |
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