Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features
Objective. This case involves a new-onset diabetes patient diagnosed during pregnancy with the congenital dysplastic right kidney. Case Report. Clinical presentation, biochemical features, imaging in a patient with diabetes diagnosed during pregnancy, and congenital dysplastic right kidney. Discussi...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2021/8243471 |
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| author | Adnan Haider Oksana Symczyk Ayesha Hassan Muhammad Atif Khan Inderpreet Madahar Dylan Holland |
| author_facet | Adnan Haider Oksana Symczyk Ayesha Hassan Muhammad Atif Khan Inderpreet Madahar Dylan Holland |
| author_sort | Adnan Haider |
| collection | DOAJ |
| description | Objective. This case involves a new-onset diabetes patient diagnosed during pregnancy with the congenital dysplastic right kidney. Case Report. Clinical presentation, biochemical features, imaging in a patient with diabetes diagnosed during pregnancy, and congenital dysplastic right kidney. Discussion. We present a case of a 22-year-old female with the congenital dysplastic right kidney diagnosed with gestational diabetes mellitus after failing a 1-hour oral glucose tolerance test, requiring insulin during pregnancy. Because of the family history of diabetes and morphologic renal abnormalities at young ages on the maternal side of the family, our patient was evaluated for maturity-onset diabetes of adult and was found to have HNF-1β mutation. Conclusion. This case highlights the importance of considering the diagnosis of maturity-onset diabetes of young and particularly MODY-5 in individuals with extrapancreatic features. MODY-5 should also be considered in a patient undergoing renal transplant at young ages with a family history of morphologic renal abnormalities. |
| format | Article |
| id | doaj-art-a779dd2aef7a41b080829c667edf91dd |
| institution | Kabale University |
| issn | 2090-651X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-a779dd2aef7a41b080829c667edf91dd2025-02-03T06:44:02ZengWileyCase Reports in Endocrinology2090-651X2021-01-01202110.1155/2021/8243471Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic FeaturesAdnan Haider0Oksana Symczyk1Ayesha Hassan2Muhammad Atif Khan3Inderpreet Madahar4Dylan Holland5600 Suncrest Towne Center600 Suncrest Towne CenterDepartment of Internal MedicineOhio State UniversityWest Virginia School of Medicine600 Suncrest Towne CenterObjective. This case involves a new-onset diabetes patient diagnosed during pregnancy with the congenital dysplastic right kidney. Case Report. Clinical presentation, biochemical features, imaging in a patient with diabetes diagnosed during pregnancy, and congenital dysplastic right kidney. Discussion. We present a case of a 22-year-old female with the congenital dysplastic right kidney diagnosed with gestational diabetes mellitus after failing a 1-hour oral glucose tolerance test, requiring insulin during pregnancy. Because of the family history of diabetes and morphologic renal abnormalities at young ages on the maternal side of the family, our patient was evaluated for maturity-onset diabetes of adult and was found to have HNF-1β mutation. Conclusion. This case highlights the importance of considering the diagnosis of maturity-onset diabetes of young and particularly MODY-5 in individuals with extrapancreatic features. MODY-5 should also be considered in a patient undergoing renal transplant at young ages with a family history of morphologic renal abnormalities.http://dx.doi.org/10.1155/2021/8243471 |
| spellingShingle | Adnan Haider Oksana Symczyk Ayesha Hassan Muhammad Atif Khan Inderpreet Madahar Dylan Holland Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features Case Reports in Endocrinology |
| title | Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features |
| title_full | Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features |
| title_fullStr | Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features |
| title_full_unstemmed | Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features |
| title_short | Maturity-Onset Diabetes of Young Type 5: Diabetes with Extrapancreatic Features |
| title_sort | maturity onset diabetes of young type 5 diabetes with extrapancreatic features |
| url | http://dx.doi.org/10.1155/2021/8243471 |
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