Changes in quality of life 5 years after sleeve gastrectomy: a prospective cohort study
Objectives Sleeve gastrectomy (SG) is the most frequently performed bariatric surgery procedure worldwide, but reports on long-term quality of life (QOL) outcomes are scarce. We investigated 5-year trajectories in QOL and their associations with weight loss after SG.Design A prospective cohort study...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2019-09-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/9/9/e031170.full |
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| author | Karl Ove Hufthammer Tone Merete Norekvål Grethe S Tell Ronette L Kolotkin Tone Nygaard Flølo Anny Aasprang Villy Våge John Roger Andersen |
| author_facet | Karl Ove Hufthammer Tone Merete Norekvål Grethe S Tell Ronette L Kolotkin Tone Nygaard Flølo Anny Aasprang Villy Våge John Roger Andersen |
| author_sort | Karl Ove Hufthammer |
| collection | DOAJ |
| description | Objectives Sleeve gastrectomy (SG) is the most frequently performed bariatric surgery procedure worldwide, but reports on long-term quality of life (QOL) outcomes are scarce. We investigated 5-year trajectories in QOL and their associations with weight loss after SG.Design A prospective cohort study.Setting The study was conducted in a single Norwegian bariatric surgery centre.Participants Out of 150 operated patients, 127 were included. Mean age was 41 years, 68% were women and the follow-up rate at 1 year was 85% and 64% at 1 and 5 years, respectively.Outcome measures Data were collected preoperatively, and 1 and 5 years after surgery assessing three different levels of QOL. The main exposure was weight loss after SG, assessed as per cent excess body mass index (kg/m2) loss (%EBMIL). The Obesity-Related Problem (OP) scale was used to measure obesity-specific health-related QOL (HRQOL). Physical (PCS) and mental (MCS) composite summary scores of the Short Form 36 Health Survey were used to capture generic HRQOL and Cantril Ladder was used to assess overall QOL.Results All HRQOL/overall QOL measures significantly improved at 1 year, followed by modest decline from 1 to 5 years after surgery. Greater %EBMIL 5 years after surgery was significantly associated with improvements in OP and PCS scores, but not with MCS and Cantril Ladder scores. Although significant (p<0.001) and clinically relevant improvements in HRQOL/overall QOL outcomes were observed at 5 years, scores were still below the general population norms.Conclusion Most patients undergoing SG experience substantial weight loss accompanied by statistically significant and clinically relevant long-term improvements in HRQOL/overall QOL. However, an important minority of patients still report low HRQOL/overall QOL 5 years after SG. Further research should aim to identify other factors that contribute to impaired QOL after bariatric surgery, even in the presence of successful weight control. |
| format | Article |
| id | doaj-art-a7739f5c0a544644abc1e5299bb6247f |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2019-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-a7739f5c0a544644abc1e5299bb6247f2025-02-02T03:10:11ZengBMJ Publishing GroupBMJ Open2044-60552019-09-019910.1136/bmjopen-2019-031170Changes in quality of life 5 years after sleeve gastrectomy: a prospective cohort studyKarl Ove Hufthammer0Tone Merete Norekvål1Grethe S Tell2Ronette L Kolotkin3Tone Nygaard Flølo4Anny Aasprang5Villy Våge6John Roger Andersen711 Centre for Clinical Research, Haukeland University Hospital, Bergen, NorwayDepartment of Clinical Science, University of Bergen, Bergen, NorwayDepartment of Global Public Health and Primary Care, University of Bergen, Bergen, Norway5 Department of Family Medicine and Community Health, Duke University School of Medicine, Durham, North Carolina, US1 Department of Surgery, Voss Hospital, Haukeland University Hospital, Voss, NorwayFaculty of Health and Social Sciences, Western Norway University of Applied Sciences—Forde Campus, Forde, Norway9 Department of Surgery, Haraldsplass Diakonale Sykehus, Bergen, NorwayFaculty of Health and Social Sciences, Western Norway University of Applied Sciences—Forde Campus, Forde, NorwayObjectives Sleeve gastrectomy (SG) is the most frequently performed bariatric surgery procedure worldwide, but reports on long-term quality of life (QOL) outcomes are scarce. We investigated 5-year trajectories in QOL and their associations with weight loss after SG.Design A prospective cohort study.Setting The study was conducted in a single Norwegian bariatric surgery centre.Participants Out of 150 operated patients, 127 were included. Mean age was 41 years, 68% were women and the follow-up rate at 1 year was 85% and 64% at 1 and 5 years, respectively.Outcome measures Data were collected preoperatively, and 1 and 5 years after surgery assessing three different levels of QOL. The main exposure was weight loss after SG, assessed as per cent excess body mass index (kg/m2) loss (%EBMIL). The Obesity-Related Problem (OP) scale was used to measure obesity-specific health-related QOL (HRQOL). Physical (PCS) and mental (MCS) composite summary scores of the Short Form 36 Health Survey were used to capture generic HRQOL and Cantril Ladder was used to assess overall QOL.Results All HRQOL/overall QOL measures significantly improved at 1 year, followed by modest decline from 1 to 5 years after surgery. Greater %EBMIL 5 years after surgery was significantly associated with improvements in OP and PCS scores, but not with MCS and Cantril Ladder scores. Although significant (p<0.001) and clinically relevant improvements in HRQOL/overall QOL outcomes were observed at 5 years, scores were still below the general population norms.Conclusion Most patients undergoing SG experience substantial weight loss accompanied by statistically significant and clinically relevant long-term improvements in HRQOL/overall QOL. However, an important minority of patients still report low HRQOL/overall QOL 5 years after SG. Further research should aim to identify other factors that contribute to impaired QOL after bariatric surgery, even in the presence of successful weight control.https://bmjopen.bmj.com/content/9/9/e031170.full |
| spellingShingle | Karl Ove Hufthammer Tone Merete Norekvål Grethe S Tell Ronette L Kolotkin Tone Nygaard Flølo Anny Aasprang Villy Våge John Roger Andersen Changes in quality of life 5 years after sleeve gastrectomy: a prospective cohort study BMJ Open |
| title | Changes in quality of life 5 years after sleeve gastrectomy: a prospective cohort study |
| title_full | Changes in quality of life 5 years after sleeve gastrectomy: a prospective cohort study |
| title_fullStr | Changes in quality of life 5 years after sleeve gastrectomy: a prospective cohort study |
| title_full_unstemmed | Changes in quality of life 5 years after sleeve gastrectomy: a prospective cohort study |
| title_short | Changes in quality of life 5 years after sleeve gastrectomy: a prospective cohort study |
| title_sort | changes in quality of life 5 years after sleeve gastrectomy a prospective cohort study |
| url | https://bmjopen.bmj.com/content/9/9/e031170.full |
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