GMP compliant simplified fast and high yielding automated synthesis of [18F]fallypride without the need of HPLC purification

GMP compliant simplified fast and high yielding automated synthesis of [18F]fallypride without the need of HPLC purification

Abstract Background [18F]Fallypride PET has been used to study D2/3 receptor occupancy and density in neuropsychiatric disorders including Huntington’s disease (HD) and aging in humans. Nevertheless, the various synthetic methods including those provided by commercial synthesizers for [18F]fallyprid...

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Bibliographic Details
Main Authors: Ammar Alfteimi, Yi Zhao, Ulf Lützen, Alexander Helm, Michael Jüptner, Maaz Zuhayra
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Automated radiosynthesis
Fallypride
D2/D3 receptors
F-18
Online Access:https://doi.org/10.1186/s41181-025-00343-w
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