Comparative physiological and cytological analysis, and omics approach provide clues to the coloring mechanism of the pumpkin yellow stems

Abstract Background The abnormal chloroplast and pigment accumulation could lead to plant yellowing. However, the plant tissue chlorisis is species-specific and could display various phenotypes due to the genetic and environmental impacts. The molecular mechanisms underlying the plant stem yellowing...

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Main Authors: Liting Deng, Jianning Luo, Haibin Wu, Xiaoxi Liu, Gangjun Zhao, Hao Gong, Xiaoming Zheng, Chaoqun Ni, Xueting Wang, Junxing Li
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Plant Biology
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Online Access:https://doi.org/10.1186/s12870-025-06673-w
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author Liting Deng
Jianning Luo
Haibin Wu
Xiaoxi Liu
Gangjun Zhao
Hao Gong
Xiaoming Zheng
Chaoqun Ni
Xueting Wang
Junxing Li
author_facet Liting Deng
Jianning Luo
Haibin Wu
Xiaoxi Liu
Gangjun Zhao
Hao Gong
Xiaoming Zheng
Chaoqun Ni
Xueting Wang
Junxing Li
author_sort Liting Deng
collection DOAJ
description Abstract Background The abnormal chloroplast and pigment accumulation could lead to plant yellowing. However, the plant tissue chlorisis is species-specific and could display various phenotypes due to the genetic and environmental impacts. The molecular mechanisms underlying the plant stem yellowing are less understood than the flower or leaf coloring mechanisms. Herein, the physiological, cytological, transcriptome analysis, along with genome-wide association study (GWAS) were integrated to illustrate the processes relevant to pumpkin stem coloring. Results Similar yet different variations were discovered in the pumpkin yellow stems. Low content of photosynthetic pigments, and impaired chloroplast thylakoid membrane were identified in the pumpkin yellowing stems, together with the presence of plastoglobules and starch grains. Elevated expression of genes in catabolism of chlorophylls and carotenoids was found in yellow stems, which may result in the failed accumulation of pigments and pumpkin stem chlorisis. Concurrently, increased expression of genes in chloroplast development, antioxidant protection, photosynthesis, and ribosome were found, which may act as compensation mechanisms for chloroplast defects. The integrated analysis of transcriptome and GWAS identified the up-regulated proteases and decreased kinesins in yellow stems, which could result in the breakdown of thylakoid systems, and the disability of photosynthetic pigments accumulation. Additionally, transcription factors could be involved in the regulation of the specific color change in pumpkin stems. Conclusions These findings provide clues into the molecular mechanisms of stem yellowing, and will facilitate the exploration of candidate targets as markers or genetic improvement through molecular breeding.
format Article
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issn 1471-2229
language English
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spelling doaj-art-a751c90feb4d4352a7e2d37fe166b3302025-08-20T01:52:22ZengBMCBMC Plant Biology1471-22292025-05-0125111710.1186/s12870-025-06673-wComparative physiological and cytological analysis, and omics approach provide clues to the coloring mechanism of the pumpkin yellow stemsLiting Deng0Jianning Luo1Haibin Wu2Xiaoxi Liu3Gangjun Zhao4Hao Gong5Xiaoming Zheng6Chaoqun Ni7Xueting Wang8Junxing Li9Guangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural SciencesGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural SciencesGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural SciencesGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural SciencesGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural SciencesGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural SciencesGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural SciencesGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural SciencesGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural SciencesGuangdong Key Laboratory for New Technology Research of Vegetables, Vegetable Research Institute, Guangdong Academy of Agricultural SciencesAbstract Background The abnormal chloroplast and pigment accumulation could lead to plant yellowing. However, the plant tissue chlorisis is species-specific and could display various phenotypes due to the genetic and environmental impacts. The molecular mechanisms underlying the plant stem yellowing are less understood than the flower or leaf coloring mechanisms. Herein, the physiological, cytological, transcriptome analysis, along with genome-wide association study (GWAS) were integrated to illustrate the processes relevant to pumpkin stem coloring. Results Similar yet different variations were discovered in the pumpkin yellow stems. Low content of photosynthetic pigments, and impaired chloroplast thylakoid membrane were identified in the pumpkin yellowing stems, together with the presence of plastoglobules and starch grains. Elevated expression of genes in catabolism of chlorophylls and carotenoids was found in yellow stems, which may result in the failed accumulation of pigments and pumpkin stem chlorisis. Concurrently, increased expression of genes in chloroplast development, antioxidant protection, photosynthesis, and ribosome were found, which may act as compensation mechanisms for chloroplast defects. The integrated analysis of transcriptome and GWAS identified the up-regulated proteases and decreased kinesins in yellow stems, which could result in the breakdown of thylakoid systems, and the disability of photosynthetic pigments accumulation. Additionally, transcription factors could be involved in the regulation of the specific color change in pumpkin stems. Conclusions These findings provide clues into the molecular mechanisms of stem yellowing, and will facilitate the exploration of candidate targets as markers or genetic improvement through molecular breeding.https://doi.org/10.1186/s12870-025-06673-wPumpkinChlorisisChloroplastChlorophyllCarotenoidPhotosynthesis
spellingShingle Liting Deng
Jianning Luo
Haibin Wu
Xiaoxi Liu
Gangjun Zhao
Hao Gong
Xiaoming Zheng
Chaoqun Ni
Xueting Wang
Junxing Li
Comparative physiological and cytological analysis, and omics approach provide clues to the coloring mechanism of the pumpkin yellow stems
BMC Plant Biology
Pumpkin
Chlorisis
Chloroplast
Chlorophyll
Carotenoid
Photosynthesis
title Comparative physiological and cytological analysis, and omics approach provide clues to the coloring mechanism of the pumpkin yellow stems
title_full Comparative physiological and cytological analysis, and omics approach provide clues to the coloring mechanism of the pumpkin yellow stems
title_fullStr Comparative physiological and cytological analysis, and omics approach provide clues to the coloring mechanism of the pumpkin yellow stems
title_full_unstemmed Comparative physiological and cytological analysis, and omics approach provide clues to the coloring mechanism of the pumpkin yellow stems
title_short Comparative physiological and cytological analysis, and omics approach provide clues to the coloring mechanism of the pumpkin yellow stems
title_sort comparative physiological and cytological analysis and omics approach provide clues to the coloring mechanism of the pumpkin yellow stems
topic Pumpkin
Chlorisis
Chloroplast
Chlorophyll
Carotenoid
Photosynthesis
url https://doi.org/10.1186/s12870-025-06673-w
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