Postoperative Thrombotic Thrombocytopenic Purpura after Total Hip Arthroplasty: A Case Report and Review of the Literature

Thrombotic thrombocytopenic purpura (TTP) is an uncommon and potentially lethal microangiopathy that carries a >90% mortality rate if not treated urgently and appropriately. Postoperative TTP after orthopaedic procedures is particularly rare with only four case reports existing in the literature....

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Main Authors: Nick N. Patel, Jason A. Shah, Christopher K. Sadlack
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2018/9716170
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author Nick N. Patel
Jason A. Shah
Christopher K. Sadlack
author_facet Nick N. Patel
Jason A. Shah
Christopher K. Sadlack
author_sort Nick N. Patel
collection DOAJ
description Thrombotic thrombocytopenic purpura (TTP) is an uncommon and potentially lethal microangiopathy that carries a >90% mortality rate if not treated urgently and appropriately. Postoperative TTP after orthopaedic procedures is particularly rare with only four case reports existing in the literature. We present the case of postoperative TTP in a 57-year-old female who underwent elective total hip arthroplasty. We believe this case adds to the limited literature surrounding the topic. While rare, TTP after orthopaedic procedures poses a real and potentially fatal condition if not managed appropriately. Therefore, it is essential for orthopaedic surgeons to be cognizant of postoperative TTP for timely diagnosis and treatment.
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spelling doaj-art-a735fe79a0364e378544ff8ab96a364e2025-08-20T02:20:38ZengWileyCase Reports in Orthopedics2090-67492090-67572018-01-01201810.1155/2018/97161709716170Postoperative Thrombotic Thrombocytopenic Purpura after Total Hip Arthroplasty: A Case Report and Review of the LiteratureNick N. Patel0Jason A. Shah1Christopher K. Sadlack2Department of Orthopaedic Surgery, Emory University School of Medicine, Atlanta, GA 30329, USADepartment of Orthopaedic Surgery, Emory University School of Medicine, Atlanta, GA 30329, USADepartment of Orthopaedic Surgery, Emory University School of Medicine, Atlanta, GA 30329, USAThrombotic thrombocytopenic purpura (TTP) is an uncommon and potentially lethal microangiopathy that carries a >90% mortality rate if not treated urgently and appropriately. Postoperative TTP after orthopaedic procedures is particularly rare with only four case reports existing in the literature. We present the case of postoperative TTP in a 57-year-old female who underwent elective total hip arthroplasty. We believe this case adds to the limited literature surrounding the topic. While rare, TTP after orthopaedic procedures poses a real and potentially fatal condition if not managed appropriately. Therefore, it is essential for orthopaedic surgeons to be cognizant of postoperative TTP for timely diagnosis and treatment.http://dx.doi.org/10.1155/2018/9716170
spellingShingle Nick N. Patel
Jason A. Shah
Christopher K. Sadlack
Postoperative Thrombotic Thrombocytopenic Purpura after Total Hip Arthroplasty: A Case Report and Review of the Literature
Case Reports in Orthopedics
title Postoperative Thrombotic Thrombocytopenic Purpura after Total Hip Arthroplasty: A Case Report and Review of the Literature
title_full Postoperative Thrombotic Thrombocytopenic Purpura after Total Hip Arthroplasty: A Case Report and Review of the Literature
title_fullStr Postoperative Thrombotic Thrombocytopenic Purpura after Total Hip Arthroplasty: A Case Report and Review of the Literature
title_full_unstemmed Postoperative Thrombotic Thrombocytopenic Purpura after Total Hip Arthroplasty: A Case Report and Review of the Literature
title_short Postoperative Thrombotic Thrombocytopenic Purpura after Total Hip Arthroplasty: A Case Report and Review of the Literature
title_sort postoperative thrombotic thrombocytopenic purpura after total hip arthroplasty a case report and review of the literature
url http://dx.doi.org/10.1155/2018/9716170
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