Identification of the potentiating mutations and synergistic epistasis that enabled the evolution of inter-species cooperation.
Microbes often engage in cooperation through releasing biosynthetic compounds required by other species to grow. Given that production of costly biosynthetic metabolites is generally subjected to multiple layers of negative feedback, single mutations may frequently be insufficient to generate cooper...
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| Main Authors: | Sarah M Douglas, Lon M Chubiz, William R Harcombe, Christopher J Marx |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0174345&type=printable |
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