Caspase 3 proteolytically inactivates gasdermin Ec and inhibits pyroptosis in an early vertebrate
Gasdermin represents a family of pore-forming proteins that execute programmed necrotic cell death, pyroptosis. As an ancient family member, gasdermin E (GSDME) exists ubiquitously from fish to mammals. Recently, a new GSDME homolog, designated GSDMEc, was identified exclusively in fish. However, th...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | Comparative Immunology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950311625000229 |
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