An overview of the feasibility of nanomedicine in pancreatic cancer theranostics
Pancreatic ductal adenocarcinoma (PDAC) is among the top causes of cancer-induced mortality, frequently diagnosed too late to be treated effectively, due to the poor prognosis and the limited successful therapeutic options. Apart from the conventional treatments, new multimodal therapies have emerge...
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| Format: | Article |
| Language: | English |
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Open Exploration Publishing Inc.
2025-06-01
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| Series: | Exploration of Targeted Anti-tumor Therapy |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A1002326/1002326.pdf |
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| author | Kyriakos Kokkinogoulis Aristomenis Kollas David Simeonidis Pavlos Papakostas Kalliopi Platoni Efstathios P. Efstathopoulos Mersini Makropoulou |
| author_facet | Kyriakos Kokkinogoulis Aristomenis Kollas David Simeonidis Pavlos Papakostas Kalliopi Platoni Efstathios P. Efstathopoulos Mersini Makropoulou |
| author_sort | Kyriakos Kokkinogoulis |
| collection | DOAJ |
| description | Pancreatic ductal adenocarcinoma (PDAC) is among the top causes of cancer-induced mortality, frequently diagnosed too late to be treated effectively, due to the poor prognosis and the limited successful therapeutic options. Apart from the conventional treatments, new multimodal therapies have emerged utilizing different scientific fields for the improvement of the survival and quality of patients’ lives. The advancement of nanotechnology leads the way to more personalized medicine and the use of targeted theranostics carriers for deep-seated cancers such as PDAC. New nanotechnology innovations such as specialized photo-sensitizing drug nanocarriers, can effectively improve photodynamic therapy (PDT) of PDAC and enhance phototherapy’s action through surface plasmon resonance phenomenon, as another recently re-emerged non- or minimally invasive possible treatment of such diseases. Despite the scientific advancements, significant hurdles remain and many parameters need to be examined. However, the novel application of nano-biophotonic techniques and the convergence of different science fields offer promise for the treatment of difficult-to-treat diseases, like PDAC. |
| format | Article |
| id | doaj-art-a71cd248346f445ca6278f8c484ac922 |
| institution | OA Journals |
| issn | 2692-3114 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Open Exploration Publishing Inc. |
| record_format | Article |
| series | Exploration of Targeted Anti-tumor Therapy |
| spelling | doaj-art-a71cd248346f445ca6278f8c484ac9222025-08-20T02:36:34ZengOpen Exploration Publishing Inc.Exploration of Targeted Anti-tumor Therapy2692-31142025-06-016100232610.37349/etat.2025.1002326An overview of the feasibility of nanomedicine in pancreatic cancer theranosticsKyriakos Kokkinogoulis0https://orcid.org/0009-0005-6478-9738Aristomenis Kollas1David Simeonidis2Pavlos Papakostas3Kalliopi Platoni4https://orcid.org/0000-0003-2977-7895Efstathios P. Efstathopoulos5https://orcid.org/0000-0003-2747-3353Mersini Makropoulou6https://orcid.org/0000-0002-3720-4862Department of Physics, Faculty of Applied Mathematical and Physical Sciences, National Technical University of Athens, 15772 Athens, Greecend Oncology Clinic, Metropolitan General, 15562 Athens, Greecend Oncology Clinic, Metropolitan General, 15562 Athens, Greecend Oncology Clinic, Metropolitan General, 15562 Athens, Greecend Department of Radiology, Medical Physics Unit, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greecend Department of Radiology, Medical Physics Unit, Medical School, National and Kapodistrian University of Athens, 12462 Athens, GreeceDepartment of Physics, Faculty of Applied Mathematical and Physical Sciences, National Technical University of Athens, 15772 Athens, GreecePancreatic ductal adenocarcinoma (PDAC) is among the top causes of cancer-induced mortality, frequently diagnosed too late to be treated effectively, due to the poor prognosis and the limited successful therapeutic options. Apart from the conventional treatments, new multimodal therapies have emerged utilizing different scientific fields for the improvement of the survival and quality of patients’ lives. The advancement of nanotechnology leads the way to more personalized medicine and the use of targeted theranostics carriers for deep-seated cancers such as PDAC. New nanotechnology innovations such as specialized photo-sensitizing drug nanocarriers, can effectively improve photodynamic therapy (PDT) of PDAC and enhance phototherapy’s action through surface plasmon resonance phenomenon, as another recently re-emerged non- or minimally invasive possible treatment of such diseases. Despite the scientific advancements, significant hurdles remain and many parameters need to be examined. However, the novel application of nano-biophotonic techniques and the convergence of different science fields offer promise for the treatment of difficult-to-treat diseases, like PDAC.https://www.explorationpub.com/uploads/Article/A1002326/1002326.pdfnanomedicinepancreatic cancerpersonalized medicinephotothermal effectphotodynamic therapyplasmonic photothermal therapy |
| spellingShingle | Kyriakos Kokkinogoulis Aristomenis Kollas David Simeonidis Pavlos Papakostas Kalliopi Platoni Efstathios P. Efstathopoulos Mersini Makropoulou An overview of the feasibility of nanomedicine in pancreatic cancer theranostics Exploration of Targeted Anti-tumor Therapy nanomedicine pancreatic cancer personalized medicine photothermal effect photodynamic therapy plasmonic photothermal therapy |
| title | An overview of the feasibility of nanomedicine in pancreatic cancer theranostics |
| title_full | An overview of the feasibility of nanomedicine in pancreatic cancer theranostics |
| title_fullStr | An overview of the feasibility of nanomedicine in pancreatic cancer theranostics |
| title_full_unstemmed | An overview of the feasibility of nanomedicine in pancreatic cancer theranostics |
| title_short | An overview of the feasibility of nanomedicine in pancreatic cancer theranostics |
| title_sort | overview of the feasibility of nanomedicine in pancreatic cancer theranostics |
| topic | nanomedicine pancreatic cancer personalized medicine photothermal effect photodynamic therapy plasmonic photothermal therapy |
| url | https://www.explorationpub.com/uploads/Article/A1002326/1002326.pdf |
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