Qilian Jiechang Ning Alleviates TNBS-Induced Ulcerative Colitis in Mice and Segatella copri Outer Membrane Vesicle-Triggered Inflammation in Colon Epithelial Cells via the Caspase-1/11-GSDMD Pathways

Qilian Jiechang Ning Alleviates TNBS-Induced Ulcerative Colitis in Mice and Segatella copri Outer Membrane Vesicle-Triggered Inflammation in Colon Epithelial Cells via the Caspase-1/11-GSDMD Pathways

Introduction: Qilian Jiechang Ning (QJN), a traditional Chinese herbal formula, has demonstrated potential therapeutic effects in the treatment of ulcerative colitis (UC). This study aims to investigate the mechanism of QJN in the outer membrane vesicles (OMVs) of Segatella copri (S. copr...

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Bibliographic Details
Main Authors: Jinyang Hu, Junjie Niu, Shisheng Jiang, Yuhua Wu
Format: Article
Language:English
Published: Karger Publishers 2025-01-01
Series:Journal of Innate Immunity
Online Access:https://karger.com/article/doi/10.1159/000545394
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