Epidemiological Study on the Prevalence and Risk Factors of Oral Premalignant Lesions in a Tertiary Care Hospital

Introduction: Oral premalignant lesions (OPLs) are precursors to oral cancer and are commonly associated with lifestyle risk factors, particularly tobacco and alcohol use. Identifying the prevalence and associated risk factors of OPLs in a tertiary care setting is crucial for developing targeted int...

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Main Authors: Neha Khaire, Janvi B. Movva, Vishwa Desai, Divya S. Gunnam, Prashant A. Karni, Ayushi Patel, Afroz Kalmee Syed
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-05-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_1441_24
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author Neha Khaire
Janvi B. Movva
Vishwa Desai
Divya S. Gunnam
Prashant A. Karni
Ayushi Patel
Afroz Kalmee Syed
author_facet Neha Khaire
Janvi B. Movva
Vishwa Desai
Divya S. Gunnam
Prashant A. Karni
Ayushi Patel
Afroz Kalmee Syed
author_sort Neha Khaire
collection DOAJ
description Introduction: Oral premalignant lesions (OPLs) are precursors to oral cancer and are commonly associated with lifestyle risk factors, particularly tobacco and alcohol use. Identifying the prevalence and associated risk factors of OPLs in a tertiary care setting is crucial for developing targeted interventions. Methods: This cross-sectional study was conducted among patients presenting to a tertiary care hospital. The prevalence of OPLs was assessed, and risk factors such as tobacco use, alcohol consumption, and betel quid chewing were evaluated. Statistical analysis was conducted to determine significant associations between risk factors and the presence of OPLs. Results: The prevalence of OPLs was found to be 7.2%, with the highest incidence among individuals with tobacco and quid-chewing habits. Statistical analysis revealed a significant association between tobacco use and the development of OPLs (P < 0.05). Conclusion: The study highlights the high prevalence of OPLs and their strong association with tobacco and quid-chewing habits. These findings emphasize the need for public health interventions targeting high-risk populations to prevent the progression of OPLs to oral cancer.
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publisher Wolters Kluwer Medknow Publications
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spelling doaj-art-a70b07967f654de18ac9edf64f4a72072025-08-20T02:34:36ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062025-05-0117Suppl 1S427S42910.4103/jpbs.jpbs_1441_24Epidemiological Study on the Prevalence and Risk Factors of Oral Premalignant Lesions in a Tertiary Care HospitalNeha KhaireJanvi B. MovvaVishwa DesaiDivya S. GunnamPrashant A. KarniAyushi PatelAfroz Kalmee SyedIntroduction: Oral premalignant lesions (OPLs) are precursors to oral cancer and are commonly associated with lifestyle risk factors, particularly tobacco and alcohol use. Identifying the prevalence and associated risk factors of OPLs in a tertiary care setting is crucial for developing targeted interventions. Methods: This cross-sectional study was conducted among patients presenting to a tertiary care hospital. The prevalence of OPLs was assessed, and risk factors such as tobacco use, alcohol consumption, and betel quid chewing were evaluated. Statistical analysis was conducted to determine significant associations between risk factors and the presence of OPLs. Results: The prevalence of OPLs was found to be 7.2%, with the highest incidence among individuals with tobacco and quid-chewing habits. Statistical analysis revealed a significant association between tobacco use and the development of OPLs (P < 0.05). Conclusion: The study highlights the high prevalence of OPLs and their strong association with tobacco and quid-chewing habits. These findings emphasize the need for public health interventions targeting high-risk populations to prevent the progression of OPLs to oral cancer.https://journals.lww.com/10.4103/jpbs.jpbs_1441_24oral premalignant lesionsprevalencequid chewingrisk factorstobacco
spellingShingle Neha Khaire
Janvi B. Movva
Vishwa Desai
Divya S. Gunnam
Prashant A. Karni
Ayushi Patel
Afroz Kalmee Syed
Epidemiological Study on the Prevalence and Risk Factors of Oral Premalignant Lesions in a Tertiary Care Hospital
Journal of Pharmacy and Bioallied Sciences
oral premalignant lesions
prevalence
quid chewing
risk factors
tobacco
title Epidemiological Study on the Prevalence and Risk Factors of Oral Premalignant Lesions in a Tertiary Care Hospital
title_full Epidemiological Study on the Prevalence and Risk Factors of Oral Premalignant Lesions in a Tertiary Care Hospital
title_fullStr Epidemiological Study on the Prevalence and Risk Factors of Oral Premalignant Lesions in a Tertiary Care Hospital
title_full_unstemmed Epidemiological Study on the Prevalence and Risk Factors of Oral Premalignant Lesions in a Tertiary Care Hospital
title_short Epidemiological Study on the Prevalence and Risk Factors of Oral Premalignant Lesions in a Tertiary Care Hospital
title_sort epidemiological study on the prevalence and risk factors of oral premalignant lesions in a tertiary care hospital
topic oral premalignant lesions
prevalence
quid chewing
risk factors
tobacco
url https://journals.lww.com/10.4103/jpbs.jpbs_1441_24
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