p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral Cancers

Background: Concerted alterations between stromal fibroblasts and neoplastic cells underline the carcinogenic process. Activation of alpha-smooth muscle actin (SMA) expression, a cytoskeleton protein normally expressed only in myoepithelial cells, is considered a landmark for the activation of strom...

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Main Authors: Ioulia Chatzistamou, Nikolina Dioufa, George Trimis, Alexandra Sklavounou, Christos Kittas, Hippokratis Kiaris, Athanasios G. Papavassiliou
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-CLO-2010-0528
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author Ioulia Chatzistamou
Nikolina Dioufa
George Trimis
Alexandra Sklavounou
Christos Kittas
Hippokratis Kiaris
Athanasios G. Papavassiliou
author_facet Ioulia Chatzistamou
Nikolina Dioufa
George Trimis
Alexandra Sklavounou
Christos Kittas
Hippokratis Kiaris
Athanasios G. Papavassiliou
author_sort Ioulia Chatzistamou
collection DOAJ
description Background: Concerted alterations between stromal fibroblasts and neoplastic cells underline the carcinogenic process. Activation of alpha-smooth muscle actin (SMA) expression, a cytoskeleton protein normally expressed only in myoepithelial cells, is considered a landmark for the activation of stromal fibroblasts with little however being known regarding the mechanism governing the expression of SMA in the stroma.
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institution Kabale University
issn 2210-7177
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language English
publishDate 2010-01-01
publisher Wiley
record_format Article
series Analytical Cellular Pathology
spelling doaj-art-a70417b984a84fb4bab01ea2a00ed6052025-08-20T03:38:49ZengWileyAnalytical Cellular Pathology2210-71772210-71852010-01-01331192610.3233/ACP-CLO-2010-0528p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral CancersIoulia Chatzistamou0Nikolina Dioufa1George Trimis2Alexandra Sklavounou3Christos Kittas4Hippokratis Kiaris5Athanasios G. Papavassiliou6Department of Basic Sciences, Dental School, University of Athens, Athens, GreeceDepartment of Biological Chemistry, Medical School, University of Athens, Athens, GreeceDepartment of Oral Medicine and Pathology, Dental School, University of Athens, Athens, GreeceDepartment of Oral Medicine and Pathology, Dental School, University of Athens, Athens, GreeceDepartment of Histology–Embryology, Medical School, University of Athens, Athens, GreeceDepartment of Biological Chemistry, Medical School, University of Athens, Athens, GreeceDepartment of Biological Chemistry, Medical School, University of Athens, Athens, GreeceBackground: Concerted alterations between stromal fibroblasts and neoplastic cells underline the carcinogenic process. Activation of alpha-smooth muscle actin (SMA) expression, a cytoskeleton protein normally expressed only in myoepithelial cells, is considered a landmark for the activation of stromal fibroblasts with little however being known regarding the mechanism governing the expression of SMA in the stroma.http://dx.doi.org/10.3233/ACP-CLO-2010-0528
spellingShingle Ioulia Chatzistamou
Nikolina Dioufa
George Trimis
Alexandra Sklavounou
Christos Kittas
Hippokratis Kiaris
Athanasios G. Papavassiliou
p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral Cancers
Analytical Cellular Pathology
title p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral Cancers
title_full p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral Cancers
title_fullStr p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral Cancers
title_full_unstemmed p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral Cancers
title_short p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral Cancers
title_sort p21 waf1 and smooth muscle actin α expression in stromal fibroblasts of oral cancers
url http://dx.doi.org/10.3233/ACP-CLO-2010-0528
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