Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults
Abstract Background: Motor Imagery (MI) represents the cognitive component of the movement and recruits dopaminergic systems. Objective: To investigate the role of dopaminergic system through the action of methylphenidate and risperidone over beta coherence during execution, action observation a...
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Thieme Revinter Publicações
2020-04-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000400199&tlng=en |
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| author | Danielle APRIGIO Guaraci Ken TANAKA Juliana BITTENCOURT Mariana GONGORA Silmar TEIXEIRA Mauricio CAGY Henning BUDDE Marco ORSINI Pedro RIBEIRO Bruna VELASQUES |
| author_facet | Danielle APRIGIO Guaraci Ken TANAKA Juliana BITTENCOURT Mariana GONGORA Silmar TEIXEIRA Mauricio CAGY Henning BUDDE Marco ORSINI Pedro RIBEIRO Bruna VELASQUES |
| author_sort | Danielle APRIGIO |
| collection | DOAJ |
| description | Abstract Background: Motor Imagery (MI) represents the cognitive component of the movement and recruits dopaminergic systems. Objective: To investigate the role of dopaminergic system through the action of methylphenidate and risperidone over beta coherence during execution, action observation and motor imagery. Methods: Electroencephalography (EEG) data were recorded before and after the substance intake. For statistical analysis, a three-way ANOVA was used to identify changes in beta coherence induced by the group, task and the moment variables. Statistical significance was set at p≤0.007. Results: We found a main effect for group for C3/CZ, and a main effect for task for CZ/C4 pairs of electrodes. Furthermore, significant differences were found in the post-drug administration between groups for C3/CZ pair of electrodes, and between task for C4/CZ pair of electrodes. Conclusion: The administration of methylphenidate and risperidone was able to produce electrocortical changes of the cortical central regions, even when featuring antagonistic effects on the dopaminergic pathways. Moreover, the execution task allowed beta-band modulation increase. |
| format | Article |
| id | doaj-art-a7006fb8bd5b44eaa471ba5d061cc90d |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publishDate | 2020-04-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-a7006fb8bd5b44eaa471ba5d061cc90d2025-08-20T02:00:45ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272020-04-0178419920510.1590/0004-282x20190186Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adultsDanielle APRIGIOhttps://orcid.org/0000-0001-5970-3497Guaraci Ken TANAKAhttps://orcid.org/0000-0001-5222-0513Juliana BITTENCOURThttps://orcid.org/0000-0003-1959-6345Mariana GONGORAhttps://orcid.org/0000-0001-9382-9958Silmar TEIXEIRAhttps://orcid.org/0000-0002-9240-1228Mauricio CAGYhttps://orcid.org/0000-0002-6488-842XHenning BUDDEhttps://orcid.org/0000-0003-3526-0569Marco ORSINIhttps://orcid.org/0000-0002-8948-3955Pedro RIBEIROhttps://orcid.org/0000-0001-8270-3663Bruna VELASQUEShttps://orcid.org/0000-0001-9363-8932Abstract Background: Motor Imagery (MI) represents the cognitive component of the movement and recruits dopaminergic systems. Objective: To investigate the role of dopaminergic system through the action of methylphenidate and risperidone over beta coherence during execution, action observation and motor imagery. Methods: Electroencephalography (EEG) data were recorded before and after the substance intake. For statistical analysis, a three-way ANOVA was used to identify changes in beta coherence induced by the group, task and the moment variables. Statistical significance was set at p≤0.007. Results: We found a main effect for group for C3/CZ, and a main effect for task for CZ/C4 pairs of electrodes. Furthermore, significant differences were found in the post-drug administration between groups for C3/CZ pair of electrodes, and between task for C4/CZ pair of electrodes. Conclusion: The administration of methylphenidate and risperidone was able to produce electrocortical changes of the cortical central regions, even when featuring antagonistic effects on the dopaminergic pathways. Moreover, the execution task allowed beta-band modulation increase.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000400199&tlng=enelectroencephalographybeta rhythmmethylphenidaterisperidonemotor imagery |
| spellingShingle | Danielle APRIGIO Guaraci Ken TANAKA Juliana BITTENCOURT Mariana GONGORA Silmar TEIXEIRA Mauricio CAGY Henning BUDDE Marco ORSINI Pedro RIBEIRO Bruna VELASQUES Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults Arquivos de Neuro-Psiquiatria electroencephalography beta rhythm methylphenidate risperidone motor imagery |
| title | Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults |
| title_full | Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults |
| title_fullStr | Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults |
| title_full_unstemmed | Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults |
| title_short | Dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults |
| title_sort | dopaminergic drugs alter beta coherence during motor imagery and motor execution in healthy adults |
| topic | electroencephalography beta rhythm methylphenidate risperidone motor imagery |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000400199&tlng=en |
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