Proteome-wide Mendelian randomization identifies causal links between blood proteins and severe COVID-19.
In November 2021, the COVID-19 pandemic death toll surpassed five million individuals. We applied Mendelian randomization including >3,000 blood proteins as exposures to identify potential biomarkers that may indicate risk for hospitalization or need for respiratory support or death due to COVID-...
Saved in:
| Main Authors: | Alish B Palmos, Vincent Millischer, David K Menon, Timothy R Nicholson, Leonie S Taams, Benedict Michael, Geraint Sunderland, Michael J Griffiths, COVID Clinical Neuroscience Study Consortium, Christopher Hübel, Gerome Breen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-03-01
|
| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010042&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases
by: Chen Li, et al.
Published: (2025-06-01) -
Using functional annotation for the empirical determination of Bayes Factors for genome-wide association study analysis.
by: Jo Knight, et al.
Published: (2011-04-01) -
Uncovering drug targets for cluster headache through proteome-wide Mendelian randomization analysis
by: Zhonghua Xiong, et al.
Published: (2025-03-01) -
Investigating causal relationships between plasma proteins and lung adenocarcinoma: result from proteomics and Mendelian randomization study
by: Ruoya Lv, et al.
Published: (2025-01-01) -
Correction: Uncovering drug targets for cluster headache through proteome-wide Mendelian randomization analysis
by: Zhonghua Xiong, et al.
Published: (2025-04-01)