Indications and outcomes of intraocular lens exchange at a tertiary ophthalmic center in Northern China from 2016 to 2024

Abstract To report the indications and outcomes of intraocular lens (IOL) exchange at a tertiary referral center in northern China over a period of 8 years. Setting: Ophthalmology departments of Hebei Eye Hospital, Hebei, China. Design: Retrospective cross-sectional study. In this retrospective stud...

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Main Authors: Zhizhong Wu, Baoyue Zhang, Zhimin Chen, Caijuan Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-02573-z
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author Zhizhong Wu
Baoyue Zhang
Zhimin Chen
Caijuan Liu
author_facet Zhizhong Wu
Baoyue Zhang
Zhimin Chen
Caijuan Liu
author_sort Zhizhong Wu
collection DOAJ
description Abstract To report the indications and outcomes of intraocular lens (IOL) exchange at a tertiary referral center in northern China over a period of 8 years. Setting: Ophthalmology departments of Hebei Eye Hospital, Hebei, China. Design: Retrospective cross-sectional study. In this retrospective study, the medical records of 233 patients with a history of IOL exchange were reviewed between 2016 and 2024. These cases were reviewed to determine surgical indications, the type of intraocular lens removed, the type of intraocular lens implanted, the time between operations, surgical complications, and visual outcomes. All postoperative data were analyzed at least six months after follow-up. The mean age of our participants was 50.05 ± 21.76 years (range 5–82 years), with a male percentage of 65.67%. The mean time between primary surgery and IOL exchange was 6.64 ± 6.16years (range 0.01–30 year). The main indications of IOL exchange were IOL dislocation (63.37%) and IOL opacification (21.81%). The most common ophthalmic comorbidity was high myopia. Procedures for secondary IOL implantation were scleral fixated IOL with sutures (34.16%), IOL in ciliary sulcus (26.75%), in-the-bag IOL (26.31%) and Iris fixation IOL (7.82%). The mean postoperative corrected distance visual acuity (CDVA) was significantly higher compared to the mean preoperative CDVA (p = 0.00). The mean preoperative and postoperative IOP were 16.23 ± 4.92 and 14.84 ± 3.05 mmHg, respectively (p = 0.00). No serious complications ware observed. IOL dislocation is the most common indication of intraocular lens implantation, followed by IOL opacification. Simultaneous scleral-sutured fixation after IOL replacement is the most common procedure in secondary IOL implantation.
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spelling doaj-art-a6fa093317c24901ac9775a8a95a195a2025-08-20T01:53:12ZengNature PortfolioScientific Reports2045-23222025-05-011511910.1038/s41598-025-02573-zIndications and outcomes of intraocular lens exchange at a tertiary ophthalmic center in Northern China from 2016 to 2024Zhizhong Wu0Baoyue Zhang1Zhimin Chen2Caijuan Liu3Hebei Provincial Key Laboratory of Ophthalmology, Department of Ophthalmology, Hebei Eye HospitalHebei Provincial Key Laboratory of Ophthalmology, Department of Ophthalmology, Hebei Eye HospitalHebei Provincial Key Laboratory of Ophthalmology, Department of Ophthalmology, Hebei Eye HospitalHebei Provincial Key Laboratory of Ophthalmology, Department of Ophthalmology, Hebei Eye HospitalAbstract To report the indications and outcomes of intraocular lens (IOL) exchange at a tertiary referral center in northern China over a period of 8 years. Setting: Ophthalmology departments of Hebei Eye Hospital, Hebei, China. Design: Retrospective cross-sectional study. In this retrospective study, the medical records of 233 patients with a history of IOL exchange were reviewed between 2016 and 2024. These cases were reviewed to determine surgical indications, the type of intraocular lens removed, the type of intraocular lens implanted, the time between operations, surgical complications, and visual outcomes. All postoperative data were analyzed at least six months after follow-up. The mean age of our participants was 50.05 ± 21.76 years (range 5–82 years), with a male percentage of 65.67%. The mean time between primary surgery and IOL exchange was 6.64 ± 6.16years (range 0.01–30 year). The main indications of IOL exchange were IOL dislocation (63.37%) and IOL opacification (21.81%). The most common ophthalmic comorbidity was high myopia. Procedures for secondary IOL implantation were scleral fixated IOL with sutures (34.16%), IOL in ciliary sulcus (26.75%), in-the-bag IOL (26.31%) and Iris fixation IOL (7.82%). The mean postoperative corrected distance visual acuity (CDVA) was significantly higher compared to the mean preoperative CDVA (p = 0.00). The mean preoperative and postoperative IOP were 16.23 ± 4.92 and 14.84 ± 3.05 mmHg, respectively (p = 0.00). No serious complications ware observed. IOL dislocation is the most common indication of intraocular lens implantation, followed by IOL opacification. Simultaneous scleral-sutured fixation after IOL replacement is the most common procedure in secondary IOL implantation.https://doi.org/10.1038/s41598-025-02573-zIndicationsIntraocular Lens exchangeIOL dislocation
spellingShingle Zhizhong Wu
Baoyue Zhang
Zhimin Chen
Caijuan Liu
Indications and outcomes of intraocular lens exchange at a tertiary ophthalmic center in Northern China from 2016 to 2024
Scientific Reports
Indications
Intraocular Lens exchange
IOL dislocation
title Indications and outcomes of intraocular lens exchange at a tertiary ophthalmic center in Northern China from 2016 to 2024
title_full Indications and outcomes of intraocular lens exchange at a tertiary ophthalmic center in Northern China from 2016 to 2024
title_fullStr Indications and outcomes of intraocular lens exchange at a tertiary ophthalmic center in Northern China from 2016 to 2024
title_full_unstemmed Indications and outcomes of intraocular lens exchange at a tertiary ophthalmic center in Northern China from 2016 to 2024
title_short Indications and outcomes of intraocular lens exchange at a tertiary ophthalmic center in Northern China from 2016 to 2024
title_sort indications and outcomes of intraocular lens exchange at a tertiary ophthalmic center in northern china from 2016 to 2024
topic Indications
Intraocular Lens exchange
IOL dislocation
url https://doi.org/10.1038/s41598-025-02573-z
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AT zhiminchen indicationsandoutcomesofintraocularlensexchangeatatertiaryophthalmiccenterinnorthernchinafrom2016to2024
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