Effectiveness of level two anomaly ultrasound scan for detection of congenital anomalies - an observational retrospective study
Objectives: This study was done to find the effectiveness of level two anomaly scan in detection of congenital anomalies and also to find the maternal and neonatal factors associated with congenital anomalies. Methods: Pregnant women with gestational age of more than or equal to 18 weeks were incl...
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Barpeta Obstetrics and Gynaecological Society
2024-12-01
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| Series: | New Indian Journal of OBGYN |
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| Online Access: | https://journal.barpetaogs.co.in/pdf/111166.pdf |
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| author | Alka S Gupta Geeta S Kulkarni Suraj D Bhame |
| author_facet | Alka S Gupta Geeta S Kulkarni Suraj D Bhame |
| author_sort | Alka S Gupta |
| collection | DOAJ |
| description | Objectives: This study was done to find the effectiveness of level two anomaly scan in detection of congenital
anomalies and also to find the maternal and neonatal factors associated with congenital anomalies. Methods:
Pregnant women with gestational age of more than or equal to 18 weeks were included in the study. All participants
were recruited when they went into labour. At the delivery of live baby, stillborn baby, abortion or after medical
termination of pregnancy, the neonate/abortus was examined and all the details were recorded and analyzed. Results:
The proportion of anomalies detected on level two anomaly scan was 7.33% and the proportion of babies with
congenital anomalies was 7.16% (n=43). The sensitivity of level two anomaly scan in detecting anomalies was
74.41% and its specificity was 97.84%. The positive predictive value of level two anomaly scan was 72.72% and its
negative predictive value was 98.02%. Percentage of false negatives was 25.58% while the percentage of false
positives was 2.15%. Anomalies of the central nervous system were the most commonly found anomalies (33.92%)
while respiratory system accounted for the least number of all anomalies (1.78%). Congenital diaphragmatic hernia
was the single most common anomaly. There was a significant difference (p<0.05) between presence of congenital
anomalies and extremes of maternal ages (weak association, CC=0.159, OR=3.7), consanguineous marriages
(moderately strong association, CC=0.292, OR=9.96) and between patients who did not take folic acid supplements in
the first and second trimester (weak association, CC=0.113, OR=3.14). Babies with congenital anomalies have higher
chances of having malpresentations (association not appreciable, CC=0.088, OR=2.9). Pregnancies with anomalous
babies had significant chances of having amniotic fluid volume changes (moderate association, CC=0.279,
OR=13.08). The association with having oligohydramnios was stronger (CC=0.238, OR=1.2) than in those having
polyhydramnios (CC=0.119, OR=10.3). Congenital anomalies significantly increased neonatal mortality rates (strong
association, CC=0.339, OR=18.94) and perinatal mortality rates (Strong association, CC=0.353, OR=16.18).
Conclusion: Level two anomaly scan should be offered to all antenatal mothers and should be used for diagnosis in
antenatal period so that preventive measures can be implemented especially in the high risk population. |
| format | Article |
| id | doaj-art-a6f64ad26b79496b9f581824cdcdc41a |
| institution | OA Journals |
| issn | 2454-2334 2454-2342 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Barpeta Obstetrics and Gynaecological Society |
| record_format | Article |
| series | New Indian Journal of OBGYN |
| spelling | doaj-art-a6f64ad26b79496b9f581824cdcdc41a2025-08-20T02:26:24ZengBarpeta Obstetrics and Gynaecological SocietyNew Indian Journal of OBGYN2454-23342454-23422024-12-0111116617310.21276/obgyn.20252024.11.1.30Effectiveness of level two anomaly ultrasound scan for detection of congenital anomalies - an observational retrospective studyAlka S Gupta0Geeta S Kulkarni1Suraj D Bhame2Professor and Head of Department, Obstetrics and Gynaecology, Topiwala National Medical College & BYL Nair Ch. Hospital, Mumbai, IndiaSenior Resident, Obstetrics and Gynaecology, Topiwala National Medical College & BYL Nair Ch. Hospital, Mumbai, India Ex Junior Resident, Obstetrics and Gynaecology, Topiwala National Medical College & BYL Nair Ch. Hospital, Mumbai, IndiaObjectives: This study was done to find the effectiveness of level two anomaly scan in detection of congenital anomalies and also to find the maternal and neonatal factors associated with congenital anomalies. Methods: Pregnant women with gestational age of more than or equal to 18 weeks were included in the study. All participants were recruited when they went into labour. At the delivery of live baby, stillborn baby, abortion or after medical termination of pregnancy, the neonate/abortus was examined and all the details were recorded and analyzed. Results: The proportion of anomalies detected on level two anomaly scan was 7.33% and the proportion of babies with congenital anomalies was 7.16% (n=43). The sensitivity of level two anomaly scan in detecting anomalies was 74.41% and its specificity was 97.84%. The positive predictive value of level two anomaly scan was 72.72% and its negative predictive value was 98.02%. Percentage of false negatives was 25.58% while the percentage of false positives was 2.15%. Anomalies of the central nervous system were the most commonly found anomalies (33.92%) while respiratory system accounted for the least number of all anomalies (1.78%). Congenital diaphragmatic hernia was the single most common anomaly. There was a significant difference (p<0.05) between presence of congenital anomalies and extremes of maternal ages (weak association, CC=0.159, OR=3.7), consanguineous marriages (moderately strong association, CC=0.292, OR=9.96) and between patients who did not take folic acid supplements in the first and second trimester (weak association, CC=0.113, OR=3.14). Babies with congenital anomalies have higher chances of having malpresentations (association not appreciable, CC=0.088, OR=2.9). Pregnancies with anomalous babies had significant chances of having amniotic fluid volume changes (moderate association, CC=0.279, OR=13.08). The association with having oligohydramnios was stronger (CC=0.238, OR=1.2) than in those having polyhydramnios (CC=0.119, OR=10.3). Congenital anomalies significantly increased neonatal mortality rates (strong association, CC=0.339, OR=18.94) and perinatal mortality rates (Strong association, CC=0.353, OR=16.18). Conclusion: Level two anomaly scan should be offered to all antenatal mothers and should be used for diagnosis in antenatal period so that preventive measures can be implemented especially in the high risk population. https://journal.barpetaogs.co.in/pdf/111166.pdfcongenital anomalies; level two anomaly ultrasound; maternal; neonatal; sensitivity; specificity |
| spellingShingle | Alka S Gupta Geeta S Kulkarni Suraj D Bhame Effectiveness of level two anomaly ultrasound scan for detection of congenital anomalies - an observational retrospective study New Indian Journal of OBGYN congenital anomalies; level two anomaly ultrasound; maternal; neonatal; sensitivity; specificity |
| title | Effectiveness of level two anomaly ultrasound scan for detection of congenital anomalies - an observational retrospective study |
| title_full | Effectiveness of level two anomaly ultrasound scan for detection of congenital anomalies - an observational retrospective study |
| title_fullStr | Effectiveness of level two anomaly ultrasound scan for detection of congenital anomalies - an observational retrospective study |
| title_full_unstemmed | Effectiveness of level two anomaly ultrasound scan for detection of congenital anomalies - an observational retrospective study |
| title_short | Effectiveness of level two anomaly ultrasound scan for detection of congenital anomalies - an observational retrospective study |
| title_sort | effectiveness of level two anomaly ultrasound scan for detection of congenital anomalies an observational retrospective study |
| topic | congenital anomalies; level two anomaly ultrasound; maternal; neonatal; sensitivity; specificity |
| url | https://journal.barpetaogs.co.in/pdf/111166.pdf |
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