Association between long-term changes in obesity-related anthropometric indicators and the risk of type 2 diabetes mellitus in the older population
Objective To investigate the association of long-term changes in body mass index, waist circumference, and waist-to-height ratio with the risk of type 2 diabetes mellitus in the older population. Methods We conducted a prospective cohort study in Jiangsu Province, China. Data from 593 participants w...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-06-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605251348229 |
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| _version_ | 1850128207684042752 |
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| author | Xiaomin Xu Lirong Li Fengmei Chen Zhirong Guo |
| author_facet | Xiaomin Xu Lirong Li Fengmei Chen Zhirong Guo |
| author_sort | Xiaomin Xu |
| collection | DOAJ |
| description | Objective To investigate the association of long-term changes in body mass index, waist circumference, and waist-to-height ratio with the risk of type 2 diabetes mellitus in the older population. Methods We conducted a prospective cohort study in Jiangsu Province, China. Data from 593 participants who were aged ≥60 years were analyzed. The hazard ratios and 95% confidence intervals were estimated using the Cox proportional hazards model. Results Over a median follow-up period of 5.08 years, 70 participants (11.80%) developed type 2 diabetes mellitus. Compared with participants with persistently normal body mass index, waist circumference, and waist-to-height ratio, those in whom these parameters changed from normal to abnormal and those in whom these parameters were persistently abnormal had a significantly higher risk of type 2 diabetes mellitus, with adjusted hazard ratios of 2.11 (95% confidence interval: 1.05–4.26) and 2.37 (95% confidence interval: 1.21–4.63) for body mass index, 2.75 (95% confidence interval: 1.16–6.51) and 2.32 (95% confidence interval: 1.29–4.16) for waist circumference, and 2.24 (95% confidence interval: 1.14–5.91) and 4.11 (95% confidence interval: 2.21–7.68) for waist-to-height ratio, respectively. Conclusion Long-term changes in obesity-related anthropometric indicators are strongly associated with the risk of type 2 diabetes mellitus in the older population. |
| format | Article |
| id | doaj-art-a6f09ec314c445d78a93ab2b78f142b3 |
| institution | OA Journals |
| issn | 1473-2300 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj-art-a6f09ec314c445d78a93ab2b78f142b32025-08-20T02:33:24ZengSAGE PublishingJournal of International Medical Research1473-23002025-06-015310.1177/03000605251348229Association between long-term changes in obesity-related anthropometric indicators and the risk of type 2 diabetes mellitus in the older populationXiaomin XuLirong LiFengmei ChenZhirong GuoObjective To investigate the association of long-term changes in body mass index, waist circumference, and waist-to-height ratio with the risk of type 2 diabetes mellitus in the older population. Methods We conducted a prospective cohort study in Jiangsu Province, China. Data from 593 participants who were aged ≥60 years were analyzed. The hazard ratios and 95% confidence intervals were estimated using the Cox proportional hazards model. Results Over a median follow-up period of 5.08 years, 70 participants (11.80%) developed type 2 diabetes mellitus. Compared with participants with persistently normal body mass index, waist circumference, and waist-to-height ratio, those in whom these parameters changed from normal to abnormal and those in whom these parameters were persistently abnormal had a significantly higher risk of type 2 diabetes mellitus, with adjusted hazard ratios of 2.11 (95% confidence interval: 1.05–4.26) and 2.37 (95% confidence interval: 1.21–4.63) for body mass index, 2.75 (95% confidence interval: 1.16–6.51) and 2.32 (95% confidence interval: 1.29–4.16) for waist circumference, and 2.24 (95% confidence interval: 1.14–5.91) and 4.11 (95% confidence interval: 2.21–7.68) for waist-to-height ratio, respectively. Conclusion Long-term changes in obesity-related anthropometric indicators are strongly associated with the risk of type 2 diabetes mellitus in the older population.https://doi.org/10.1177/03000605251348229 |
| spellingShingle | Xiaomin Xu Lirong Li Fengmei Chen Zhirong Guo Association between long-term changes in obesity-related anthropometric indicators and the risk of type 2 diabetes mellitus in the older population Journal of International Medical Research |
| title | Association between long-term changes in obesity-related anthropometric indicators and the risk of type 2 diabetes mellitus in the older population |
| title_full | Association between long-term changes in obesity-related anthropometric indicators and the risk of type 2 diabetes mellitus in the older population |
| title_fullStr | Association between long-term changes in obesity-related anthropometric indicators and the risk of type 2 diabetes mellitus in the older population |
| title_full_unstemmed | Association between long-term changes in obesity-related anthropometric indicators and the risk of type 2 diabetes mellitus in the older population |
| title_short | Association between long-term changes in obesity-related anthropometric indicators and the risk of type 2 diabetes mellitus in the older population |
| title_sort | association between long term changes in obesity related anthropometric indicators and the risk of type 2 diabetes mellitus in the older population |
| url | https://doi.org/10.1177/03000605251348229 |
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