Management and Prevention of Herpes Zoster: A Canadian Perspective
Varicella-zoster virus reactivation leads to herpes zoster – the main complication of which is postherpetic neuralgia (PHN). Rapid antiviral therapy initiated within 72 h of rash onset has been shown to accelerate rash healing, reduce the duration of acute pain and, to some extent, attenuate the dev...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2010/178036 |
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| _version_ | 1849397788915269632 |
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| author | Guy Boivin Roman Jovey Catherine T Elliott David M Patrick |
| author_facet | Guy Boivin Roman Jovey Catherine T Elliott David M Patrick |
| author_sort | Guy Boivin |
| collection | DOAJ |
| description | Varicella-zoster virus reactivation leads to herpes zoster – the main complication of which is postherpetic neuralgia (PHN). Rapid antiviral therapy initiated within 72 h of rash onset has been shown to accelerate rash healing, reduce the duration of acute pain and, to some extent, attenuate the development and duration of PHN. Other adjunctive therapies such as analgesics, antidepressants and some anticonvulsants are frequently required in the management of severe PHN. A live, attenuated zoster vaccine has been recently shown to significantly decrease herpes zoster incidence, PHN and the overall burden of illness when administered to adults older than 60 years of age. This new prophylactic modality has been reported to be cost-effective in the Canadian context, especially in the 60- to 75-year-old age group. |
| format | Article |
| id | doaj-art-a6ea7e2b9f074de3a9dfde707a89a9ff |
| institution | Kabale University |
| issn | 1712-9532 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-a6ea7e2b9f074de3a9dfde707a89a9ff2025-08-20T03:38:50ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322010-01-01211455210.1155/2010/178036Management and Prevention of Herpes Zoster: A Canadian PerspectiveGuy Boivin0Roman Jovey1Catherine T Elliott2David M Patrick3Research Centre in Infectious Diseases of the Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Quebec, CanadaCentres for Pain Management, Mississauga, Ontario, CanadaBC Centre for Disease Control and University of British Columbia, Vancouver, British Columbia, CanadaBC Centre for Disease Control and University of British Columbia, Vancouver, British Columbia, CanadaVaricella-zoster virus reactivation leads to herpes zoster – the main complication of which is postherpetic neuralgia (PHN). Rapid antiviral therapy initiated within 72 h of rash onset has been shown to accelerate rash healing, reduce the duration of acute pain and, to some extent, attenuate the development and duration of PHN. Other adjunctive therapies such as analgesics, antidepressants and some anticonvulsants are frequently required in the management of severe PHN. A live, attenuated zoster vaccine has been recently shown to significantly decrease herpes zoster incidence, PHN and the overall burden of illness when administered to adults older than 60 years of age. This new prophylactic modality has been reported to be cost-effective in the Canadian context, especially in the 60- to 75-year-old age group.http://dx.doi.org/10.1155/2010/178036 |
| spellingShingle | Guy Boivin Roman Jovey Catherine T Elliott David M Patrick Management and Prevention of Herpes Zoster: A Canadian Perspective Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Management and Prevention of Herpes Zoster: A Canadian Perspective |
| title_full | Management and Prevention of Herpes Zoster: A Canadian Perspective |
| title_fullStr | Management and Prevention of Herpes Zoster: A Canadian Perspective |
| title_full_unstemmed | Management and Prevention of Herpes Zoster: A Canadian Perspective |
| title_short | Management and Prevention of Herpes Zoster: A Canadian Perspective |
| title_sort | management and prevention of herpes zoster a canadian perspective |
| url | http://dx.doi.org/10.1155/2010/178036 |
| work_keys_str_mv | AT guyboivin managementandpreventionofherpeszosteracanadianperspective AT romanjovey managementandpreventionofherpeszosteracanadianperspective AT catherinetelliott managementandpreventionofherpeszosteracanadianperspective AT davidmpatrick managementandpreventionofherpeszosteracanadianperspective |