Understanding Cognition, Oxytocin, and Pain in Elders (UCOPE): protocol for a double-blinded cross-over trial in chronic knee osteoarthritis pain

Understanding Cognition, Oxytocin, and Pain in Elders (UCOPE): protocol for a double-blinded cross-over trial in chronic knee osteoarthritis pain

Abstract Background Osteoarthritis (OA) is the leading cause of disability among older adults with the knee being the most affected joint. Specifically, there is an urgent need to develop better analgesics for individuals with OA-related pain, since currently used analgesics frequently fail to provi...

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Bibliographic Details
Main Authors: Yenisel Cruz-Almeida, Soamy Montesino-Goicolea, Pedro Valdes-Hernandez, Zhiguang Huo, Roland Staud, Natalie C. Ebner
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Trials
Subjects:
Aging
Disability
Knee osteoarthritis pain
Brain
Oxytocin
Randomized controlled trial
Online Access:https://doi.org/10.1186/s13063-024-08715-4
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