Mesenchymal stem cells improve ovarian function by suppressing fibrosis through CTGF/FAK signalling in systemic lupus erythematosus

Mesenchymal stem cells improve ovarian function by suppressing fibrosis through CTGF/FAK signalling in systemic lupus erythematosus

Objective SLE is a multisystem autoimmune disease characterised by chronic inflammation and progressive organ damage, including ovarian dysfunction. This study investigated the therapeutic efficacy of umbilical cord-derived mesenchymal stem cells (UC-MSCs) in ameliorating ovarian impairment and rest...

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Bibliographic Details
Main Authors: Min Xu, Hui Yang, Lingyun Sun, Hongwei Chen, Yueyang Zhang, Haiwei Zhang, Yingyi Wu, Yirui Shi
Format: Article
Language:English
Published: BMJ Publishing Group 2025-08-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/12/2/e001468.full
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