Trends in Antimicrobial Resistance of Canine Otitis Pathogens in the Iberian Peninsula (2010–2021)
<b>Background</b>: The close relationship between humans and petsraises health concerns due to the potential transmission of antimicrobial-resistant (AMR) bacteria and genes. Bacterial otitis is an emerging health problem in dogs, given its widespread prevalence and impact on animal welf...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-03-01
|
| Series: | Antibiotics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6382/14/4/328 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849712341196734464 |
|---|---|
| author | Biel Garcias Mar Batalla Anna Vidal Inma Durán Laila Darwich |
| author_facet | Biel Garcias Mar Batalla Anna Vidal Inma Durán Laila Darwich |
| author_sort | Biel Garcias |
| collection | DOAJ |
| description | <b>Background</b>: The close relationship between humans and petsraises health concerns due to the potential transmission of antimicrobial-resistant (AMR) bacteria and genes. Bacterial otitis is an emerging health problem in dogs, given its widespread prevalence and impact on animal welfare. Early detection of resistance is vital in veterinary medicine to anticipate future treatment challenges. <b>Objective</b>: This study aimed to determine the prevalence of AMR bacteria involved in 12,498 cases of otitis in dogs from the Iberian Peninsula and the evolution of AMR patterns over an 11-year period. <b>Methods</b>: Data was provided by the Veterinary Medicine Department of a large private diagnostic laboratory in Barcelona. Antimicrobial susceptibility testing was performed using the standard disk diffusion method and minimum inhibitory concentration (MIC) testing. <b>Results</b>: The frequency of the principal bacterial agents was 35% <i>Staphylococcus</i> spp. (principally <i>S. pseudointermedius</i>), 20% <i>Pseudomonas</i> spp. (<i>P. aeruginosa</i>), 13% <i>Streptococcus</i> spp. (<i>S. canis</i>), and 11% Enterobacterales (<i>Escherichia coli</i> and <i>Proteus mirabilis</i>). Antimicrobial susceptibility testing revealed <i>P. aeruginosa</i> (among Gram-negatives) and <i>Enterococcus faecalis</i> (among Gram-positives) as the species with the highest AMR to multiple antimicrobial classes throughout the years. According to the frequency and time evolution of multidrug resistance (MDR), Gram-negative bacteria like <i>P. mirabilis</i> (33%) and <i>E. coli</i> (25%) presented higher MDR rates compared to Gram-positive strains like <i>Corynebacterium</i> (7%) and <i>Enterococcus</i> (5%). The AMR evolution also showed an increase in resistance patterns in <i>Proteus</i> spp. to doxycycline and <i>Streptococcus</i> spp. to amikacin. <b>Conclusions</b>: This information can be useful for clinicians, particularly in this region, to make rational antimicrobial use decisions, especially when empirical treatment is common in companion animal veterinary medicine. In summary, improving treatment guidelines is a key strategy for safeguarding both animal and human health, reinforcing the One Health approach. |
| format | Article |
| id | doaj-art-a6e214fd39e94f069c29cf4cc50b1666 |
| institution | DOAJ |
| issn | 2079-6382 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj-art-a6e214fd39e94f069c29cf4cc50b16662025-08-20T03:14:17ZengMDPI AGAntibiotics2079-63822025-03-0114432810.3390/antibiotics14040328Trends in Antimicrobial Resistance of Canine Otitis Pathogens in the Iberian Peninsula (2010–2021)Biel Garcias0Mar Batalla1Anna Vidal2Inma Durán3Laila Darwich4Department of Sanitat i Anatomia Animals, Veterinary Faculty, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, SpainDepartment of Sanitat i Anatomia Animals, Veterinary Faculty, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, SpainDepartment of Sanitat i Anatomia Animals, Veterinary Faculty, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, SpainDepartamento de Veterinaria de Laboratorios Echevarne, 08037 Barcelona, SpainDepartment of Sanitat i Anatomia Animals, Veterinary Faculty, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, Spain<b>Background</b>: The close relationship between humans and petsraises health concerns due to the potential transmission of antimicrobial-resistant (AMR) bacteria and genes. Bacterial otitis is an emerging health problem in dogs, given its widespread prevalence and impact on animal welfare. Early detection of resistance is vital in veterinary medicine to anticipate future treatment challenges. <b>Objective</b>: This study aimed to determine the prevalence of AMR bacteria involved in 12,498 cases of otitis in dogs from the Iberian Peninsula and the evolution of AMR patterns over an 11-year period. <b>Methods</b>: Data was provided by the Veterinary Medicine Department of a large private diagnostic laboratory in Barcelona. Antimicrobial susceptibility testing was performed using the standard disk diffusion method and minimum inhibitory concentration (MIC) testing. <b>Results</b>: The frequency of the principal bacterial agents was 35% <i>Staphylococcus</i> spp. (principally <i>S. pseudointermedius</i>), 20% <i>Pseudomonas</i> spp. (<i>P. aeruginosa</i>), 13% <i>Streptococcus</i> spp. (<i>S. canis</i>), and 11% Enterobacterales (<i>Escherichia coli</i> and <i>Proteus mirabilis</i>). Antimicrobial susceptibility testing revealed <i>P. aeruginosa</i> (among Gram-negatives) and <i>Enterococcus faecalis</i> (among Gram-positives) as the species with the highest AMR to multiple antimicrobial classes throughout the years. According to the frequency and time evolution of multidrug resistance (MDR), Gram-negative bacteria like <i>P. mirabilis</i> (33%) and <i>E. coli</i> (25%) presented higher MDR rates compared to Gram-positive strains like <i>Corynebacterium</i> (7%) and <i>Enterococcus</i> (5%). The AMR evolution also showed an increase in resistance patterns in <i>Proteus</i> spp. to doxycycline and <i>Streptococcus</i> spp. to amikacin. <b>Conclusions</b>: This information can be useful for clinicians, particularly in this region, to make rational antimicrobial use decisions, especially when empirical treatment is common in companion animal veterinary medicine. In summary, improving treatment guidelines is a key strategy for safeguarding both animal and human health, reinforcing the One Health approach.https://www.mdpi.com/2079-6382/14/4/328antimicrobial resistanceotitisdogsIberian Peninsula |
| spellingShingle | Biel Garcias Mar Batalla Anna Vidal Inma Durán Laila Darwich Trends in Antimicrobial Resistance of Canine Otitis Pathogens in the Iberian Peninsula (2010–2021) Antibiotics antimicrobial resistance otitis dogs Iberian Peninsula |
| title | Trends in Antimicrobial Resistance of Canine Otitis Pathogens in the Iberian Peninsula (2010–2021) |
| title_full | Trends in Antimicrobial Resistance of Canine Otitis Pathogens in the Iberian Peninsula (2010–2021) |
| title_fullStr | Trends in Antimicrobial Resistance of Canine Otitis Pathogens in the Iberian Peninsula (2010–2021) |
| title_full_unstemmed | Trends in Antimicrobial Resistance of Canine Otitis Pathogens in the Iberian Peninsula (2010–2021) |
| title_short | Trends in Antimicrobial Resistance of Canine Otitis Pathogens in the Iberian Peninsula (2010–2021) |
| title_sort | trends in antimicrobial resistance of canine otitis pathogens in the iberian peninsula 2010 2021 |
| topic | antimicrobial resistance otitis dogs Iberian Peninsula |
| url | https://www.mdpi.com/2079-6382/14/4/328 |
| work_keys_str_mv | AT bielgarcias trendsinantimicrobialresistanceofcanineotitispathogensintheiberianpeninsula20102021 AT marbatalla trendsinantimicrobialresistanceofcanineotitispathogensintheiberianpeninsula20102021 AT annavidal trendsinantimicrobialresistanceofcanineotitispathogensintheiberianpeninsula20102021 AT inmaduran trendsinantimicrobialresistanceofcanineotitispathogensintheiberianpeninsula20102021 AT lailadarwich trendsinantimicrobialresistanceofcanineotitispathogensintheiberianpeninsula20102021 |