Importance of Diversity in the Oral Microbiota including Candida Species Revealed by High-Throughput Technologies
Taking advantage of high-throughput technologies, deep sequencing of the human microbiome has revealed commensal bacteria independent of the ability to culture them. The composition of the commensal microbiome is dependent on bacterial diversity and the state of the host regulated by the immune syst...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2014/454391 |
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| author | Tamaki Cho Jun-ichi Nagao Rieko Imayoshi Yoshihiko Tanaka |
| author_facet | Tamaki Cho Jun-ichi Nagao Rieko Imayoshi Yoshihiko Tanaka |
| author_sort | Tamaki Cho |
| collection | DOAJ |
| description | Taking advantage of high-throughput technologies, deep sequencing of the human microbiome has revealed commensal bacteria independent of the ability to culture them. The composition of the commensal microbiome is dependent on bacterial diversity and the state of the host regulated by the immune system. Candida species are well known as components of the commensal oral microbiota. Candida species frequently colonize and develop biofilms on medical devices like dentures and catheters. Therefore, Candida biofilm on dentures leads to a decrease in the bacterial diversity and then to a change in the composition of the oral microbiota. A disturbance in the balance between commensal bacteria and the host immune system results in a switch from a healthy state to a diseased state even in the limited oral niche. |
| format | Article |
| id | doaj-art-a6deabebc83b4057b43398aa0aa51422 |
| institution | Kabale University |
| issn | 1687-8728 1687-8736 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-a6deabebc83b4057b43398aa0aa514222025-02-03T01:21:24ZengWileyInternational Journal of Dentistry1687-87281687-87362014-01-01201410.1155/2014/454391454391Importance of Diversity in the Oral Microbiota including Candida Species Revealed by High-Throughput TechnologiesTamaki Cho0Jun-ichi Nagao1Rieko Imayoshi2Yoshihiko Tanaka3Section of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, JapanSection of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, JapanSection of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, JapanSection of Infection Biology, Department of Functional Bioscience, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, JapanTaking advantage of high-throughput technologies, deep sequencing of the human microbiome has revealed commensal bacteria independent of the ability to culture them. The composition of the commensal microbiome is dependent on bacterial diversity and the state of the host regulated by the immune system. Candida species are well known as components of the commensal oral microbiota. Candida species frequently colonize and develop biofilms on medical devices like dentures and catheters. Therefore, Candida biofilm on dentures leads to a decrease in the bacterial diversity and then to a change in the composition of the oral microbiota. A disturbance in the balance between commensal bacteria and the host immune system results in a switch from a healthy state to a diseased state even in the limited oral niche.http://dx.doi.org/10.1155/2014/454391 |
| spellingShingle | Tamaki Cho Jun-ichi Nagao Rieko Imayoshi Yoshihiko Tanaka Importance of Diversity in the Oral Microbiota including Candida Species Revealed by High-Throughput Technologies International Journal of Dentistry |
| title | Importance of Diversity in the Oral Microbiota including Candida Species Revealed by High-Throughput Technologies |
| title_full | Importance of Diversity in the Oral Microbiota including Candida Species Revealed by High-Throughput Technologies |
| title_fullStr | Importance of Diversity in the Oral Microbiota including Candida Species Revealed by High-Throughput Technologies |
| title_full_unstemmed | Importance of Diversity in the Oral Microbiota including Candida Species Revealed by High-Throughput Technologies |
| title_short | Importance of Diversity in the Oral Microbiota including Candida Species Revealed by High-Throughput Technologies |
| title_sort | importance of diversity in the oral microbiota including candida species revealed by high throughput technologies |
| url | http://dx.doi.org/10.1155/2014/454391 |
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