Comparative analysis of S100A10 and S100A11 in MASLD and hepatic cancer development revealed a tumor suppressive role for S100A10

Abstract S100 proteins are significantly deregulated in hepatocellular carcinoma (HCC) and metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we investigated the impact of hepatocyte downregulation of two closely-related members of the S100 family, S100A10 and S100A11, in comple...

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Main Authors: Etienne Delangre, Marta Correia de Sousa, Miranda Türkal, Monika Gjorgjieva, Suzanne Chartier, Grégoire Arnoux, Cyril Sobolewski, Margot Fournier, Christine Maeder, Laura Rubbia-Brandt, Pierre Maechler, Michelangelo Foti
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07940-2
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