4-(1<i>H</i>-Tetrazol-5-yl)-2-(<i>p</i>-tolyl)quinoline

4-(1<i>H</i>-Tetrazol-5-yl)-2-(<i>p</i>-tolyl)quinoline

The synthesis of 4-(1<i>H</i>-tetrazol-5-yl)-2-(<i>p</i>-tolyl)quinoline <b>4</b> as a possible modification of the biphenyltetrazole substructure of losartan <b>1</b> is described. The transformation of 2-(<i>p</i>-tolyl)quinoline-4-carbon...

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Bibliographic Details
Main Authors: Angelika Lásiková, Daniel Végh
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Molbank
Subjects:
angiotensin II receptor antagonists
analog of losartan
2,4-disubstituted quinoline
synthesis of tetrazolylquinoline
Online Access:https://www.mdpi.com/1422-8599/2024/4/M1897
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