The effect of immobilization and surgery stress on serum ghrelin level, body weight, and food consumption in male rats
Background: In our daily life, we encounter with various types of stress. These stresses result to different autonomic, hormonal, and behavioral responses. One of the hormones that its secretion is affected by stress is called ghrelin. The aim of this study was to investigate the effect of immobiliz...
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Iran Air Force Health Administration
2015-10-01
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| Series: | فصلنامه ابن سینا |
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| Online Access: | http://ebnesina.ajaums.ac.ir/article-1-240-en.pdf |
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| author | P Zareian A Mozafar H Kargar Jahromi |
| author_facet | P Zareian A Mozafar H Kargar Jahromi |
| author_sort | P Zareian |
| collection | DOAJ |
| description | Background: In our daily life, we encounter with various types of stress. These stresses result to different autonomic, hormonal, and behavioral responses. One of the hormones that its secretion is affected by stress is called ghrelin. The aim of this study was to investigate the effect of immobilization and surgery stress on serum ghrelin level, food consumption, and body weight in male rats.
Materials and methods: Forty Sprague Dawley male rats (200-220 g weight) were used. The serum ghrelin level (via Elisa method), food consumption (with daily measurement), and changes in body weight (in seven days) were measured following the surgery and immobilization stress. Also, body weight was measured in the first and 7th day.
Results: Compared to the control group, immobilization stress caused a significant increase in the level of serum ghrelin (56.8±8.5 vs. 31.7±3.7 pg/ml (and food consumption (371.3 vs. 287±11 g). The increase of body weight was lower than the control group (2.3±1 vs. 12±2 g). It was interesting to note that the surgical stress had no significant effect on the serum ghrelin level, food consumption, and body weight.
Conclusion: In this work, only the stress of immobilization caused a significant change on the serum ghrelin level, food consumption, and body weight; so it seems that the effect of stress on these factors depends on the kind of stress. |
| format | Article |
| id | doaj-art-a6c9d7bea5914341b366fd6755a4aecd |
| institution | OA Journals |
| issn | 1735-9503 2645-4653 |
| language | fas |
| publishDate | 2015-10-01 |
| publisher | Iran Air Force Health Administration |
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| series | فصلنامه ابن سینا |
| spelling | doaj-art-a6c9d7bea5914341b366fd6755a4aecd2025-08-20T01:58:11ZfasIran Air Force Health Administrationفصلنامه ابن سینا1735-95032645-46532015-10-01173510The effect of immobilization and surgery stress on serum ghrelin level, body weight, and food consumption in male ratsP Zareian0A Mozafar1H Kargar Jahromi2 Department of physiology, AJA University of Medical Science, Tehran, Iran Department of biology, Jahrom branch, Islamic Azad University, Jahrom, Iran Department of physiology, Jahrom branch, Islamic Azad University, Jahrom, Iran Background: In our daily life, we encounter with various types of stress. These stresses result to different autonomic, hormonal, and behavioral responses. One of the hormones that its secretion is affected by stress is called ghrelin. The aim of this study was to investigate the effect of immobilization and surgery stress on serum ghrelin level, food consumption, and body weight in male rats. Materials and methods: Forty Sprague Dawley male rats (200-220 g weight) were used. The serum ghrelin level (via Elisa method), food consumption (with daily measurement), and changes in body weight (in seven days) were measured following the surgery and immobilization stress. Also, body weight was measured in the first and 7th day. Results: Compared to the control group, immobilization stress caused a significant increase in the level of serum ghrelin (56.8±8.5 vs. 31.7±3.7 pg/ml (and food consumption (371.3 vs. 287±11 g). The increase of body weight was lower than the control group (2.3±1 vs. 12±2 g). It was interesting to note that the surgical stress had no significant effect on the serum ghrelin level, food consumption, and body weight. Conclusion: In this work, only the stress of immobilization caused a significant change on the serum ghrelin level, food consumption, and body weight; so it seems that the effect of stress on these factors depends on the kind of stress.http://ebnesina.ajaums.ac.ir/article-1-240-en.pdfphysiological stressesoperative surgical proceduresimmobilizationghrelinbody weight |
| spellingShingle | P Zareian A Mozafar H Kargar Jahromi The effect of immobilization and surgery stress on serum ghrelin level, body weight, and food consumption in male rats فصلنامه ابن سینا physiological stresses operative surgical procedures immobilization ghrelin body weight |
| title | The effect of immobilization and surgery stress on serum ghrelin level, body weight, and food consumption in male rats |
| title_full | The effect of immobilization and surgery stress on serum ghrelin level, body weight, and food consumption in male rats |
| title_fullStr | The effect of immobilization and surgery stress on serum ghrelin level, body weight, and food consumption in male rats |
| title_full_unstemmed | The effect of immobilization and surgery stress on serum ghrelin level, body weight, and food consumption in male rats |
| title_short | The effect of immobilization and surgery stress on serum ghrelin level, body weight, and food consumption in male rats |
| title_sort | effect of immobilization and surgery stress on serum ghrelin level body weight and food consumption in male rats |
| topic | physiological stresses operative surgical procedures immobilization ghrelin body weight |
| url | http://ebnesina.ajaums.ac.ir/article-1-240-en.pdf |
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