High heritability is compatible with the broad distribution of set point viral load in HIV carriers.

Set point viral load in HIV patients ranges over several orders of magnitude and is a key determinant of disease progression in HIV. A number of recent studies have reported high heritability of set point viral load implying that viral genetic factors contribute substantially to the overall variatio...

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Bibliographic Details
Main Authors: Sebastian Bonhoeffer, Christophe Fraser, Gabriel E Leventhal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004634&type=printable
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