COLA-GLM: collaborative one-shot and lossless algorithms of generalized linear models for decentralized observational healthcare data

COLA-GLM: collaborative one-shot and lossless algorithms of generalized linear models for decentralized observational healthcare data

Abstract Clinical insights from real-world data often require aggregating information from institutions to ensure sufficient sample sizes and generalizability. However, patient privacy concerns only limit the sharing of patient-level data, and traditional federated learning algorithms, relying on ex...

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Main Authors: Qiong Wu, Jenna M. Reps, Lu Li, Bingyu Zhang, Yiwen Lu, Jiayi Tong, Dazheng Zhang, Thomas Lumley, Milou T. Brand, Mui Van Zandt, Thomas Falconer, Xing He, Yu Huang, Haoyang Li, Chao Yan, Guojun Tang, Andrew E. Williams, Fei Wang, Jiang Bian, Bradley Malin, George Hripcsak, Martijn J. Schuemie, Yun Lu, Steve Drew, Jiayu Zhou, David A. Asch, Yong Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-025-01781-1
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