Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic Neuralgia
This study aimed to explore the application value of nalbuphine in pulsed radiofrequency operation of trigeminal ganglion in patients with postherpetic neuralgia (PHN). Thirty patients with PHN were randomly divided into the nalbuphine (Nalbu) group and ketorolac tromethamine (KT) group and received...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2021/6623112 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850169280759332864 |
|---|---|
| author | Song Wen Qiu-Xia Xiao Zhao-Qiong Zhu Li Chen Ying Li Qi-Hua Ran Song Cao Liu-Lin Xiong |
| author_facet | Song Wen Qiu-Xia Xiao Zhao-Qiong Zhu Li Chen Ying Li Qi-Hua Ran Song Cao Liu-Lin Xiong |
| author_sort | Song Wen |
| collection | DOAJ |
| description | This study aimed to explore the application value of nalbuphine in pulsed radiofrequency operation of trigeminal ganglion in patients with postherpetic neuralgia (PHN). Thirty patients with PHN were randomly divided into the nalbuphine (Nalbu) group and ketorolac tromethamine (KT) group and received CT-guided pulsed radiofrequency surgery on trigeminal ganglion. The numeric rating scale (NRS) scores of patients were recorded at preoperative, intraoperative, and postoperative time points, before going to bed, and the next morning after the operation. In addition, the number of breakthrough pain before operation and within 24 hours after operation, the incidence of nausea and vomiting within 24 hours after surgery, and the patient’s sleep quality before and on the day after surgery were evaluated. The outcome data demonstrated that patients treated with nalbuphine had lower NRS scores after the pulse radiofrequency operation during and after the pulse radiofrequency operation compared to those with KT. In addition, nalbuphine effectively decreased the number of breakthrough pain, reduced the occurrence of nausea and vomiting after surgery, and improved the sleep quality. In conclusion, intramuscular injection of nalbuphine 30 min before trigeminal ganglion pulse radiofrequency surgery can be conducive to pain relief and improve the postoperative comfort of patients, providing an effective alternative for the alleviation of PHN in clinic. |
| format | Article |
| id | doaj-art-a6a1a5ca78bc47d38428ecd2ce1ea1b2 |
| institution | OA Journals |
| issn | 1203-6765 1918-1523 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-a6a1a5ca78bc47d38428ecd2ce1ea1b22025-08-20T02:20:45ZengWileyPain Research and Management1203-67651918-15232021-01-01202110.1155/2021/66231126623112Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic NeuralgiaSong Wen0Qiu-Xia Xiao1Zhao-Qiong Zhu2Li Chen3Ying Li4Qi-Hua Ran5Song Cao6Liu-Lin Xiong7Department of Anesthesiology, Department of Pain Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, ChinaSouthwest Medical University, Luzhou 646000, ChinaDepartment of Anesthesiology, Department of Pain Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, ChinaInstitute of Neurological Disease, West China Hospital, Sichuan University, Chengdu 610041, ChinaDepartment of Anesthesiology, Department of Pain Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, ChinaDepartment of Anesthesiology, Department of Pain Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, ChinaDepartment of Anesthesiology, Department of Pain Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, ChinaDepartment of Anesthesiology, Department of Pain Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, ChinaThis study aimed to explore the application value of nalbuphine in pulsed radiofrequency operation of trigeminal ganglion in patients with postherpetic neuralgia (PHN). Thirty patients with PHN were randomly divided into the nalbuphine (Nalbu) group and ketorolac tromethamine (KT) group and received CT-guided pulsed radiofrequency surgery on trigeminal ganglion. The numeric rating scale (NRS) scores of patients were recorded at preoperative, intraoperative, and postoperative time points, before going to bed, and the next morning after the operation. In addition, the number of breakthrough pain before operation and within 24 hours after operation, the incidence of nausea and vomiting within 24 hours after surgery, and the patient’s sleep quality before and on the day after surgery were evaluated. The outcome data demonstrated that patients treated with nalbuphine had lower NRS scores after the pulse radiofrequency operation during and after the pulse radiofrequency operation compared to those with KT. In addition, nalbuphine effectively decreased the number of breakthrough pain, reduced the occurrence of nausea and vomiting after surgery, and improved the sleep quality. In conclusion, intramuscular injection of nalbuphine 30 min before trigeminal ganglion pulse radiofrequency surgery can be conducive to pain relief and improve the postoperative comfort of patients, providing an effective alternative for the alleviation of PHN in clinic.http://dx.doi.org/10.1155/2021/6623112 |
| spellingShingle | Song Wen Qiu-Xia Xiao Zhao-Qiong Zhu Li Chen Ying Li Qi-Hua Ran Song Cao Liu-Lin Xiong Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic Neuralgia Pain Research and Management |
| title | Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic Neuralgia |
| title_full | Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic Neuralgia |
| title_fullStr | Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic Neuralgia |
| title_full_unstemmed | Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic Neuralgia |
| title_short | Application of Nalbuphine in Trigeminal Ganglion Pulse Radiofrequency Surgery in Patients with Postherpetic Neuralgia |
| title_sort | application of nalbuphine in trigeminal ganglion pulse radiofrequency surgery in patients with postherpetic neuralgia |
| url | http://dx.doi.org/10.1155/2021/6623112 |
| work_keys_str_mv | AT songwen applicationofnalbuphineintrigeminalganglionpulseradiofrequencysurgeryinpatientswithpostherpeticneuralgia AT qiuxiaxiao applicationofnalbuphineintrigeminalganglionpulseradiofrequencysurgeryinpatientswithpostherpeticneuralgia AT zhaoqiongzhu applicationofnalbuphineintrigeminalganglionpulseradiofrequencysurgeryinpatientswithpostherpeticneuralgia AT lichen applicationofnalbuphineintrigeminalganglionpulseradiofrequencysurgeryinpatientswithpostherpeticneuralgia AT yingli applicationofnalbuphineintrigeminalganglionpulseradiofrequencysurgeryinpatientswithpostherpeticneuralgia AT qihuaran applicationofnalbuphineintrigeminalganglionpulseradiofrequencysurgeryinpatientswithpostherpeticneuralgia AT songcao applicationofnalbuphineintrigeminalganglionpulseradiofrequencysurgeryinpatientswithpostherpeticneuralgia AT liulinxiong applicationofnalbuphineintrigeminalganglionpulseradiofrequencysurgeryinpatientswithpostherpeticneuralgia |