The “L-Sandwich” Strategy for True Coronary Bifurcation Lesions: A Randomized Clinical Trial
Background. This study explored the efficacy of the “L-sandwich” strategy, which involves the implantation of stents in the main vessel (MV) and shaft of the side branch (SB) with a drug-coated balloon (DCB) applied to the SB ostium, for coronary true bifurcation lesions. Methods and Results. Of 99...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Journal of Interventional Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2023/6889836 |
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| author | Quan Guo Liang Peng Lixin Rao Cao Ma Kang Zhao Zhenzhou Zhao Haiyu Tang Muwei Li |
| author_facet | Quan Guo Liang Peng Lixin Rao Cao Ma Kang Zhao Zhenzhou Zhao Haiyu Tang Muwei Li |
| author_sort | Quan Guo |
| collection | DOAJ |
| description | Background. This study explored the efficacy of the “L-sandwich” strategy, which involves the implantation of stents in the main vessel (MV) and shaft of the side branch (SB) with a drug-coated balloon (DCB) applied to the SB ostium, for coronary true bifurcation lesions. Methods and Results. Of 99 patients with true bifurcation lesions, 38 patients underwent the “L-sandwich” strategy (group A), 32 patients underwent a two-stent strategy (group B), and 29 patients underwent a single-stent + DCB strategy (group C). Angiography outcomes (late lumen loss [LLL], minimum lumen diameter [MLD]), and clinical outcomes (major adverse cardiac events [MACEs]) were analyzed. At 6 months, the MLD of the SB ostium in groups A and B were similar (P>0.05) and group A larger than group C (P<0.05). The LLL of group B was the largest among the three groups (P<0.05). The MLD of the SB shaft in groups A and B were larger than in group C (P<0.05). The LLL of the SB shaft in group C was the lowest (P<0.05). Two patients in group B received target vessel revascularization at the 6-month followup (P>0.05), and patients in the other groups had no MACEs. Conclusions. The “L-sandwich” strategy was feasible for the treatment of true coronary bifurcation lesions. It is a simpler procedure with similar acute lumen gain than the two-stent strategy, results in a larger SB lumen than the single-stent + DCB strategy, and it can also be used as a remedy for dissection following the single-stent + DCB strategy. |
| format | Article |
| id | doaj-art-a6a01ac457b648a68c3f928233b83941 |
| institution | Kabale University |
| issn | 1540-8183 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Interventional Cardiology |
| spelling | doaj-art-a6a01ac457b648a68c3f928233b839412025-01-24T00:00:01ZengWileyJournal of Interventional Cardiology1540-81832023-01-01202310.1155/2023/6889836The “L-Sandwich” Strategy for True Coronary Bifurcation Lesions: A Randomized Clinical TrialQuan Guo0Liang Peng1Lixin Rao2Cao Ma3Kang Zhao4Zhenzhou Zhao5Haiyu Tang6Muwei Li7Department of CardiologyDepartment of Coronary Heart Disease of Central China Fuwai HospitalDepartment of Coronary Heart Disease of Central China Fuwai HospitalDepartment of Coronary Heart Disease of Central China Fuwai HospitalDepartment of Coronary Heart Disease of Central China Fuwai HospitalDepartment of Coronary Heart Disease of Central China Fuwai HospitalDepartment of Coronary Heart Disease of Central China Fuwai HospitalDepartment of CardiologyBackground. This study explored the efficacy of the “L-sandwich” strategy, which involves the implantation of stents in the main vessel (MV) and shaft of the side branch (SB) with a drug-coated balloon (DCB) applied to the SB ostium, for coronary true bifurcation lesions. Methods and Results. Of 99 patients with true bifurcation lesions, 38 patients underwent the “L-sandwich” strategy (group A), 32 patients underwent a two-stent strategy (group B), and 29 patients underwent a single-stent + DCB strategy (group C). Angiography outcomes (late lumen loss [LLL], minimum lumen diameter [MLD]), and clinical outcomes (major adverse cardiac events [MACEs]) were analyzed. At 6 months, the MLD of the SB ostium in groups A and B were similar (P>0.05) and group A larger than group C (P<0.05). The LLL of group B was the largest among the three groups (P<0.05). The MLD of the SB shaft in groups A and B were larger than in group C (P<0.05). The LLL of the SB shaft in group C was the lowest (P<0.05). Two patients in group B received target vessel revascularization at the 6-month followup (P>0.05), and patients in the other groups had no MACEs. Conclusions. The “L-sandwich” strategy was feasible for the treatment of true coronary bifurcation lesions. It is a simpler procedure with similar acute lumen gain than the two-stent strategy, results in a larger SB lumen than the single-stent + DCB strategy, and it can also be used as a remedy for dissection following the single-stent + DCB strategy.http://dx.doi.org/10.1155/2023/6889836 |
| spellingShingle | Quan Guo Liang Peng Lixin Rao Cao Ma Kang Zhao Zhenzhou Zhao Haiyu Tang Muwei Li The “L-Sandwich” Strategy for True Coronary Bifurcation Lesions: A Randomized Clinical Trial Journal of Interventional Cardiology |
| title | The “L-Sandwich” Strategy for True Coronary Bifurcation Lesions: A Randomized Clinical Trial |
| title_full | The “L-Sandwich” Strategy for True Coronary Bifurcation Lesions: A Randomized Clinical Trial |
| title_fullStr | The “L-Sandwich” Strategy for True Coronary Bifurcation Lesions: A Randomized Clinical Trial |
| title_full_unstemmed | The “L-Sandwich” Strategy for True Coronary Bifurcation Lesions: A Randomized Clinical Trial |
| title_short | The “L-Sandwich” Strategy for True Coronary Bifurcation Lesions: A Randomized Clinical Trial |
| title_sort | l sandwich strategy for true coronary bifurcation lesions a randomized clinical trial |
| url | http://dx.doi.org/10.1155/2023/6889836 |
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