Type 2 diabetes and colorectal cancer: genetic causality explored via Mendelian randomization

Type 2 diabetes and colorectal cancer: genetic causality explored via Mendelian randomization

Abstract Background The global burden of type 2 diabetes (T2D) and colorectal cancer (CRC) continues to rise. Observational studies have suggested a link between T2D and an elevated risk of CRC. However, these studies are often susceptible to confounding factors and reverse causation, leading to inc...

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Bibliographic Details
Main Authors: Qiuhong Ke, Yongbing Huang, Libin Cheng, Chaolin Lin, Linhua Zhao, Wulong Huang, Zhisheng Chen, Yimin Xu, Yipiao Huang, Lanlan Cai, Bin Lin, Rui Tang
Format: Article
Language:English
Published: Springer 2024-11-01
Series:Discover Oncology
Subjects:
Diabetes mellitus
Type 2
Colorectal neoplasms
Mendelian randomization analysis
Genome-wide association study
Causality
Online Access:https://doi.org/10.1007/s12672-024-01621-w
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