Adrenalectomy improves MSG-induced obesity in rats by increasing UCP-1 levels in interscapular brown adipose tissue

Adrenalectomy improves MSG-induced obesity in rats by increasing UCP-1 levels in interscapular brown adipose tissue

The administration of monosodium glutamate (MSG) to neonates has been shown to result in hypothalamic damage and development of metabolic syndrome. The objective of this study was to investigate whether bilateral adrenalectomy (ADX) could alter sympathetic activity in adult MSG rats, with the poten...

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Bibliographic Details
Main Authors: Willian Nascimento de Souza Rodrigues, Ananda Malta, Naiara Cristina Lucredi, Patrícia Cristina Lisboa, Rosiane Aparecida Miranda, Rodrigo Vargas, Camila Benan Zara, Maria Natália Chimirri Peres, Nilton Rodrigues Teixeira Junior, Jurandir Fernando Comar, Paulo Cezar de Freitas Mathias, Rosana Torrezan
Format: Article
Language:English
Published: Universidade Estadual de Maringá 2025-01-01
Series:Acta Scientiarum: Biological Sciences
Subjects:
MSG rats; fructosamine; iBAT; adipose tissue harvesting; TyG index; β3 - adrenergic receptor pathway
Online Access:https://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/72713
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