Biological and Mechanical Factors and Epigenetic Regulation Involved in Tendon Healing
Tendons are an important part of the musculoskeletal system. Connecting muscles to bones, tendons convert force into movement. Tendon injury can be acute or chronic. Noticeably, tendon healing requires a long time span and includes inflammation, proliferation, and remodeling processes. The mismatch...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2023/4387630 |
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| _version_ | 1832551133624664064 |
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| author | Zhi Jie Li Qian Qian Yang You Lang Zhou |
| author_facet | Zhi Jie Li Qian Qian Yang You Lang Zhou |
| author_sort | Zhi Jie Li |
| collection | DOAJ |
| description | Tendons are an important part of the musculoskeletal system. Connecting muscles to bones, tendons convert force into movement. Tendon injury can be acute or chronic. Noticeably, tendon healing requires a long time span and includes inflammation, proliferation, and remodeling processes. The mismatch between endogenous and exogenous healing may lead to adhesion causing further negative effects. Management of tendon injuries and complications such as subsequent adhesion formation are still challenges for clinicians. Due to numerous factors, tendon healing is a complex process. This review introduces the role of various biological and mechanical factors and epigenetic regulation processes involved in tendon healing. |
| format | Article |
| id | doaj-art-a68508f3182d45aea78a31c593a5f643 |
| institution | Kabale University |
| issn | 1687-9678 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-a68508f3182d45aea78a31c593a5f6432025-02-03T06:04:50ZengWileyStem Cells International1687-96782023-01-01202310.1155/2023/4387630Biological and Mechanical Factors and Epigenetic Regulation Involved in Tendon HealingZhi Jie Li0Qian Qian Yang1You Lang Zhou2Hand Surgery Research CenterHand Surgery Research CenterHand Surgery Research CenterTendons are an important part of the musculoskeletal system. Connecting muscles to bones, tendons convert force into movement. Tendon injury can be acute or chronic. Noticeably, tendon healing requires a long time span and includes inflammation, proliferation, and remodeling processes. The mismatch between endogenous and exogenous healing may lead to adhesion causing further negative effects. Management of tendon injuries and complications such as subsequent adhesion formation are still challenges for clinicians. Due to numerous factors, tendon healing is a complex process. This review introduces the role of various biological and mechanical factors and epigenetic regulation processes involved in tendon healing.http://dx.doi.org/10.1155/2023/4387630 |
| spellingShingle | Zhi Jie Li Qian Qian Yang You Lang Zhou Biological and Mechanical Factors and Epigenetic Regulation Involved in Tendon Healing Stem Cells International |
| title | Biological and Mechanical Factors and Epigenetic Regulation Involved in Tendon Healing |
| title_full | Biological and Mechanical Factors and Epigenetic Regulation Involved in Tendon Healing |
| title_fullStr | Biological and Mechanical Factors and Epigenetic Regulation Involved in Tendon Healing |
| title_full_unstemmed | Biological and Mechanical Factors and Epigenetic Regulation Involved in Tendon Healing |
| title_short | Biological and Mechanical Factors and Epigenetic Regulation Involved in Tendon Healing |
| title_sort | biological and mechanical factors and epigenetic regulation involved in tendon healing |
| url | http://dx.doi.org/10.1155/2023/4387630 |
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