Separation and purification of flavonoids from different citrus fruits and their antioxidant activities

Representative varieties of six different citrus types including ‘Yuhuan Wendan’ (pomelo), ‘Huyou’ (grapefruit), ‘Lunwan navel orange’ (sweet orange), ‘Daidai’ (bitter orange), ‘Ougan’ (mandarin) and ‘Ponkan’ (tangerine) were selected as materials. The main antioxidant active substances of different...

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Main Authors: ZHU Tailin, WANG Huixin, CHEN Jiebiao, WANG Yue, CAO Jinping, LI Xian, SUN Chongde
Format: Article
Language:English
Published: Zhejiang University Press 2021-12-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/j.issn.1008-9209.2021.06.152
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author ZHU Tailin
WANG Huixin
CHEN Jiebiao
WANG Yue
CAO Jinping
LI Xian
SUN Chongde
author_facet ZHU Tailin
WANG Huixin
CHEN Jiebiao
WANG Yue
CAO Jinping
LI Xian
SUN Chongde
author_sort ZHU Tailin
collection DOAJ
description Representative varieties of six different citrus types including ‘Yuhuan Wendan’ (pomelo), ‘Huyou’ (grapefruit), ‘Lunwan navel orange’ (sweet orange), ‘Daidai’ (bitter orange), ‘Ougan’ (mandarin) and ‘Ponkan’ (tangerine) were selected as materials. The main antioxidant active substances of different citrus varieties were identified and purified. The antioxidant activities of citrus extracts from different varieties were compared. By establishing a step-fraction extraction method and purification system, compositions of flavones, flavanones and polymethoxylated flavonoids were purified simultaneously, and 15 monomers were acquired. The results showed that the chemical antioxidant capacities of different segmented products and purified monomers were quite different. The fraction products dominated by flavonoids and flavanones had strong antioxidant capacities, while the fraction products dominated by polymethoxylated flavonoids had poor antioxidant capacities. The flavonoids from the pomelo variety ‘Yuhuan Wendan’ and purities were vicenin-2 (98.72%), rhoifolin (95.78%) and naringin (99.56%); the flavonoids from the grapefruit variety ‘Huyou’ and purities were narirutin-4<inline-formula><alternatives><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M2"><mml:mi mathvariant="normal">´</mml:mi></mml:math><inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/D22CD70C-54A1-45f9-9DB5-9678C570CD24-M002.jpg"/></alternatives></inline-formula>-O-glucoside (98.42%), eriocitrin (98.74%) and neoeriocitrin (99.17%); the flavonoid from the sweet orange variety ‘Lunwan navel orange’ and purity was narirutin (98.12%); the flavonoid from the tangerine variety ‘Ponkan’ and the purity was hesperidin (98.00%); the flavonoids from the mandarin variety ‘Ougan’ and purities were neohesperidin (98.56%), poncirin (98.03%), isosinensetin (98.76%), sinensetin (98.77%), nobiletin (99.15%), tangeretin (99.20%) and 5-demethylnobiletin (97.63%). Among the purified monomers, the antioxidant capacities of neoeriocitrin, eriocitrin, hesperidin and neohesperidin were stronger, and they were poorer for nobiletin and tangeretin.
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series 浙江大学学报. 农业与生命科学版
spelling doaj-art-a67f995c740941ec8995a82f7b77d7402025-08-20T03:32:05ZengZhejiang University Press浙江大学学报. 农业与生命科学版1008-92092097-51552021-12-014770471810.3785/j.issn.1008-9209.2021.06.15210089209Separation and purification of flavonoids from different citrus fruits and their antioxidant activitiesZHU TailinWANG HuixinCHEN JiebiaoWANG YueCAO JinpingLI XianSUN ChongdeRepresentative varieties of six different citrus types including ‘Yuhuan Wendan’ (pomelo), ‘Huyou’ (grapefruit), ‘Lunwan navel orange’ (sweet orange), ‘Daidai’ (bitter orange), ‘Ougan’ (mandarin) and ‘Ponkan’ (tangerine) were selected as materials. The main antioxidant active substances of different citrus varieties were identified and purified. The antioxidant activities of citrus extracts from different varieties were compared. By establishing a step-fraction extraction method and purification system, compositions of flavones, flavanones and polymethoxylated flavonoids were purified simultaneously, and 15 monomers were acquired. The results showed that the chemical antioxidant capacities of different segmented products and purified monomers were quite different. The fraction products dominated by flavonoids and flavanones had strong antioxidant capacities, while the fraction products dominated by polymethoxylated flavonoids had poor antioxidant capacities. The flavonoids from the pomelo variety ‘Yuhuan Wendan’ and purities were vicenin-2 (98.72%), rhoifolin (95.78%) and naringin (99.56%); the flavonoids from the grapefruit variety ‘Huyou’ and purities were narirutin-4<inline-formula><alternatives><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M2"><mml:mi mathvariant="normal">´</mml:mi></mml:math><inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/D22CD70C-54A1-45f9-9DB5-9678C570CD24-M002.jpg"/></alternatives></inline-formula>-O-glucoside (98.42%), eriocitrin (98.74%) and neoeriocitrin (99.17%); the flavonoid from the sweet orange variety ‘Lunwan navel orange’ and purity was narirutin (98.12%); the flavonoid from the tangerine variety ‘Ponkan’ and the purity was hesperidin (98.00%); the flavonoids from the mandarin variety ‘Ougan’ and purities were neohesperidin (98.56%), poncirin (98.03%), isosinensetin (98.76%), sinensetin (98.77%), nobiletin (99.15%), tangeretin (99.20%) and 5-demethylnobiletin (97.63%). Among the purified monomers, the antioxidant capacities of neoeriocitrin, eriocitrin, hesperidin and neohesperidin were stronger, and they were poorer for nobiletin and tangeretin.https://www.academax.com/doi/10.3785/j.issn.1008-9209.2021.06.152citrusflavonoidspurificationantioxidation
spellingShingle ZHU Tailin
WANG Huixin
CHEN Jiebiao
WANG Yue
CAO Jinping
LI Xian
SUN Chongde
Separation and purification of flavonoids from different citrus fruits and their antioxidant activities
浙江大学学报. 农业与生命科学版
citrus
flavonoids
purification
antioxidation
title Separation and purification of flavonoids from different citrus fruits and their antioxidant activities
title_full Separation and purification of flavonoids from different citrus fruits and their antioxidant activities
title_fullStr Separation and purification of flavonoids from different citrus fruits and their antioxidant activities
title_full_unstemmed Separation and purification of flavonoids from different citrus fruits and their antioxidant activities
title_short Separation and purification of flavonoids from different citrus fruits and their antioxidant activities
title_sort separation and purification of flavonoids from different citrus fruits and their antioxidant activities
topic citrus
flavonoids
purification
antioxidation
url https://www.academax.com/doi/10.3785/j.issn.1008-9209.2021.06.152
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AT wanghuixin separationandpurificationofflavonoidsfromdifferentcitrusfruitsandtheirantioxidantactivities
AT chenjiebiao separationandpurificationofflavonoidsfromdifferentcitrusfruitsandtheirantioxidantactivities
AT wangyue separationandpurificationofflavonoidsfromdifferentcitrusfruitsandtheirantioxidantactivities
AT caojinping separationandpurificationofflavonoidsfromdifferentcitrusfruitsandtheirantioxidantactivities
AT lixian separationandpurificationofflavonoidsfromdifferentcitrusfruitsandtheirantioxidantactivities
AT sunchongde separationandpurificationofflavonoidsfromdifferentcitrusfruitsandtheirantioxidantactivities