Adult-onset Still’s disease in pregnancy: case report and literature review

Background: Adult-onset Still’s disease (AOSD) is a clinical syndrome whose etiology and pathogenesis remain unclear. The clinical symptoms of AOSD mainly include fever, erythema, arthralgia and muscle pain, which cannot be diagnosed by specific auxiliary examination and can initially attack during...

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Main Authors: Liang Chao, Li Jia, Ke-Fang Wang
Format: Article
Language:English
Published: IMR Press 2021-06-01
Series:Clinical and Experimental Obstetrics & Gynecology
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Online Access:https://www.imrpress.com/journal/CEOG/48/3/10.31083/j.ceog.2021.03.2153
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author Liang Chao
Li Jia
Ke-Fang Wang
author_facet Liang Chao
Li Jia
Ke-Fang Wang
author_sort Liang Chao
collection DOAJ
description Background: Adult-onset Still’s disease (AOSD) is a clinical syndrome whose etiology and pathogenesis remain unclear. The clinical symptoms of AOSD mainly include fever, erythema, arthralgia and muscle pain, which cannot be diagnosed by specific auxiliary examination and can initially attack during pregnancy. The identification of the disease is revealed by a diagnosis of exclusion. Currently, the relationship between pregnancy and AOSD remains unclear. Here, we report on one case of AOSD during pregnancy that was admitted to the Beijing Anzhen Hospital affiliated to Capital Medical University. A 24-year-old woman was admitted to hospital due to intermittent fever, a history of pain and swelling of the large joints at 33 weeks gestation. After the diagnosis of AOSD, the symptoms relieved with medication. The patient delivered a premature, 3450 g baby successfully. Conclusions: The diagnostic criteria of pregnancy complicated by AOSD mainly depends on a diagnosis of exclusion. The literature both at home and abroad shows that the onset of AOSD is closely related to pregnancy, and that pregnancy is one of its predisposing factors. Its clinical manifestations are arthritis, arthromyalgia, fever, pharyngitis and so on, which involve multiple systems. There is no highly specific approach available in the laboratory examination and imaging for this disease.
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spelling doaj-art-a67e538b3c4e4f729921a4c8378f62572025-08-20T03:48:35ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632021-06-0148370070610.31083/j.ceog.2021.03.2153S0390-6663(21)00184-6Adult-onset Still’s disease in pregnancy: case report and literature reviewLiang Chao0Li Jia1Ke-Fang Wang2Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, ChinaBeijing Anzhen Hospital, Capital Medical University, 100029 Beijing, ChinaBeijing Anzhen Hospital, Capital Medical University, 100029 Beijing, ChinaBackground: Adult-onset Still’s disease (AOSD) is a clinical syndrome whose etiology and pathogenesis remain unclear. The clinical symptoms of AOSD mainly include fever, erythema, arthralgia and muscle pain, which cannot be diagnosed by specific auxiliary examination and can initially attack during pregnancy. The identification of the disease is revealed by a diagnosis of exclusion. Currently, the relationship between pregnancy and AOSD remains unclear. Here, we report on one case of AOSD during pregnancy that was admitted to the Beijing Anzhen Hospital affiliated to Capital Medical University. A 24-year-old woman was admitted to hospital due to intermittent fever, a history of pain and swelling of the large joints at 33 weeks gestation. After the diagnosis of AOSD, the symptoms relieved with medication. The patient delivered a premature, 3450 g baby successfully. Conclusions: The diagnostic criteria of pregnancy complicated by AOSD mainly depends on a diagnosis of exclusion. The literature both at home and abroad shows that the onset of AOSD is closely related to pregnancy, and that pregnancy is one of its predisposing factors. Its clinical manifestations are arthritis, arthromyalgia, fever, pharyngitis and so on, which involve multiple systems. There is no highly specific approach available in the laboratory examination and imaging for this disease.https://www.imrpress.com/journal/CEOG/48/3/10.31083/j.ceog.2021.03.2153adult-onset still's diseaseaosdpregnancy
spellingShingle Liang Chao
Li Jia
Ke-Fang Wang
Adult-onset Still’s disease in pregnancy: case report and literature review
Clinical and Experimental Obstetrics & Gynecology
adult-onset still's disease
aosd
pregnancy
title Adult-onset Still’s disease in pregnancy: case report and literature review
title_full Adult-onset Still’s disease in pregnancy: case report and literature review
title_fullStr Adult-onset Still’s disease in pregnancy: case report and literature review
title_full_unstemmed Adult-onset Still’s disease in pregnancy: case report and literature review
title_short Adult-onset Still’s disease in pregnancy: case report and literature review
title_sort adult onset still s disease in pregnancy case report and literature review
topic adult-onset still's disease
aosd
pregnancy
url https://www.imrpress.com/journal/CEOG/48/3/10.31083/j.ceog.2021.03.2153
work_keys_str_mv AT liangchao adultonsetstillsdiseaseinpregnancycasereportandliteraturereview
AT lijia adultonsetstillsdiseaseinpregnancycasereportandliteraturereview
AT kefangwang adultonsetstillsdiseaseinpregnancycasereportandliteraturereview