Multivessel Coronary Artery Vasospasm-Induced Takotsubo Cardiomyopathy
Takotsubo cardiomyopathy is associated with a constellation of cardiac findings including reversible left ventricular dysfunction and an acute triggering stressor. Epicardial coronary vasospasm is a rarely reported etiology for takotsubo cardiomyopathy, and its pathophysiologic mechanisms still rema...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2022/2192863 |
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| _version_ | 1832549460601733120 |
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| author | Vishal I. Patel Serap Sobnosky |
| author_facet | Vishal I. Patel Serap Sobnosky |
| author_sort | Vishal I. Patel |
| collection | DOAJ |
| description | Takotsubo cardiomyopathy is associated with a constellation of cardiac findings including reversible left ventricular dysfunction and an acute triggering stressor. Epicardial coronary vasospasm is a rarely reported etiology for takotsubo cardiomyopathy, and its pathophysiologic mechanisms still remain incompletely understood. We present the case of a 54-year-old female with chest pain and ST-elevation myocardial infarction who was found to have takotsubo cardiomyopathy due to diffuse multivessel coronary artery vasospasm in the absence of obstructive coronary artery disease. To our knowledge, this is the first angiographically confirmed case of this rare phenomenon to be reported, as most literature involves focal, segmental, or single coronary artery involvement. Moreover, we review current literature and develop a discussion on the targeted treatment of vasospastic disease as part of the multimodal approach to the management of takotsubo syndrome. |
| format | Article |
| id | doaj-art-a66e3a49208748bdbb72c294122976b3 |
| institution | Kabale University |
| issn | 2090-6412 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-a66e3a49208748bdbb72c294122976b32025-02-03T06:11:19ZengWileyCase Reports in Cardiology2090-64122022-01-01202210.1155/2022/2192863Multivessel Coronary Artery Vasospasm-Induced Takotsubo CardiomyopathyVishal I. Patel0Serap Sobnosky1St. Mary Medical CenterSt. Mary Medical CenterTakotsubo cardiomyopathy is associated with a constellation of cardiac findings including reversible left ventricular dysfunction and an acute triggering stressor. Epicardial coronary vasospasm is a rarely reported etiology for takotsubo cardiomyopathy, and its pathophysiologic mechanisms still remain incompletely understood. We present the case of a 54-year-old female with chest pain and ST-elevation myocardial infarction who was found to have takotsubo cardiomyopathy due to diffuse multivessel coronary artery vasospasm in the absence of obstructive coronary artery disease. To our knowledge, this is the first angiographically confirmed case of this rare phenomenon to be reported, as most literature involves focal, segmental, or single coronary artery involvement. Moreover, we review current literature and develop a discussion on the targeted treatment of vasospastic disease as part of the multimodal approach to the management of takotsubo syndrome.http://dx.doi.org/10.1155/2022/2192863 |
| spellingShingle | Vishal I. Patel Serap Sobnosky Multivessel Coronary Artery Vasospasm-Induced Takotsubo Cardiomyopathy Case Reports in Cardiology |
| title | Multivessel Coronary Artery Vasospasm-Induced Takotsubo Cardiomyopathy |
| title_full | Multivessel Coronary Artery Vasospasm-Induced Takotsubo Cardiomyopathy |
| title_fullStr | Multivessel Coronary Artery Vasospasm-Induced Takotsubo Cardiomyopathy |
| title_full_unstemmed | Multivessel Coronary Artery Vasospasm-Induced Takotsubo Cardiomyopathy |
| title_short | Multivessel Coronary Artery Vasospasm-Induced Takotsubo Cardiomyopathy |
| title_sort | multivessel coronary artery vasospasm induced takotsubo cardiomyopathy |
| url | http://dx.doi.org/10.1155/2022/2192863 |
| work_keys_str_mv | AT vishalipatel multivesselcoronaryarteryvasospasminducedtakotsubocardiomyopathy AT serapsobnosky multivesselcoronaryarteryvasospasminducedtakotsubocardiomyopathy |