The Mechanism and Inflammatory Markers Involved in the Potential Use of N-acetylcysteine in Chronic Pain Management

The Mechanism and Inflammatory Markers Involved in the Potential Use of N-acetylcysteine in Chronic Pain Management

N-acetylcysteine (NAC) has established use as an antidote for acetaminophen overdose and treatment for pulmonary conditions and nephropathy. It plays a role in regulating oxidative stress and interacting with various cytokines including IL-1β, TNFα, IL-8, IL-6, IL-10, and NF-κB p65. The overexpressi...

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Bibliographic Details
Main Authors: Mona Singh, Alina Kim, Amelie Young, Deanna Nguyen, Cynthia L. Monroe, Tiffany Ding, Dennis Gray, Vishwanath Venketaraman
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Life
Subjects:
NAC
neuropathic pain
musculoskeletal pain
opioids
metalloproteinases
ROS
Online Access:https://www.mdpi.com/2075-1729/14/11/1361
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