Bullous Lichen Planus Treated with Adalimumab: A Case Report
Introduction: Bullous lichen planus is a rare variant of lichen planus that is characterized by vesiculobullous lesions developing in the setting of preexisting LP lesions with a burning and painful feeling. Bullous lichen planus treatment is difficult since so few examples of the conditi...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2025-01-01
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| Series: | Case Reports in Dermatology |
| Online Access: | https://karger.com/article/doi/10.1159/000543523 |
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| author | Bashayr S. Alhubayshi Abdulaziz A. Alnoshan Ahmed A. AlHumidi Asem Shadid |
| author_facet | Bashayr S. Alhubayshi Abdulaziz A. Alnoshan Ahmed A. AlHumidi Asem Shadid |
| author_sort | Bashayr S. Alhubayshi |
| collection | DOAJ |
| description |
Introduction: Bullous lichen planus is a rare variant of lichen planus that is characterized by vesiculobullous lesions developing in the setting of preexisting LP lesions with a burning and painful feeling. Bullous lichen planus treatment is difficult since so few examples of the condition have been documented in the literature. Case Presentation: A 46-year-old female presented to our outpatient clinic with pruritic violaceous bullae involving lower extremities and oral mucosa for 8 years. After extensive investigations, a diagnosis of bullous lichen planus was made and successfully treated with adalimumab after failure of other treatment options. Conclusion: Adalimumab may represent a promising, efficacious, and safe monotherapy option for the management of bullous lichen planus. The therapeutic value of this novel off-label use should be assessed in controlled clinical trials. |
| format | Article |
| id | doaj-art-a64e7fe4efd44713b2ef864fe654eff5 |
| institution | Kabale University |
| issn | 1662-6567 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Dermatology |
| spelling | doaj-art-a64e7fe4efd44713b2ef864fe654eff52025-08-20T03:49:42ZengKarger PublishersCase Reports in Dermatology1662-65672025-01-01171424710.1159/000543523Bullous Lichen Planus Treated with Adalimumab: A Case ReportBashayr S. AlhubayshiAbdulaziz A. AlnoshanAhmed A. AlHumidiAsem Shadid Introduction: Bullous lichen planus is a rare variant of lichen planus that is characterized by vesiculobullous lesions developing in the setting of preexisting LP lesions with a burning and painful feeling. Bullous lichen planus treatment is difficult since so few examples of the condition have been documented in the literature. Case Presentation: A 46-year-old female presented to our outpatient clinic with pruritic violaceous bullae involving lower extremities and oral mucosa for 8 years. After extensive investigations, a diagnosis of bullous lichen planus was made and successfully treated with adalimumab after failure of other treatment options. Conclusion: Adalimumab may represent a promising, efficacious, and safe monotherapy option for the management of bullous lichen planus. The therapeutic value of this novel off-label use should be assessed in controlled clinical trials. https://karger.com/article/doi/10.1159/000543523 |
| spellingShingle | Bashayr S. Alhubayshi Abdulaziz A. Alnoshan Ahmed A. AlHumidi Asem Shadid Bullous Lichen Planus Treated with Adalimumab: A Case Report Case Reports in Dermatology |
| title | Bullous Lichen Planus Treated with Adalimumab: A Case Report |
| title_full | Bullous Lichen Planus Treated with Adalimumab: A Case Report |
| title_fullStr | Bullous Lichen Planus Treated with Adalimumab: A Case Report |
| title_full_unstemmed | Bullous Lichen Planus Treated with Adalimumab: A Case Report |
| title_short | Bullous Lichen Planus Treated with Adalimumab: A Case Report |
| title_sort | bullous lichen planus treated with adalimumab a case report |
| url | https://karger.com/article/doi/10.1159/000543523 |
| work_keys_str_mv | AT bashayrsalhubayshi bullouslichenplanustreatedwithadalimumabacasereport AT abdulazizaalnoshan bullouslichenplanustreatedwithadalimumabacasereport AT ahmedaalhumidi bullouslichenplanustreatedwithadalimumabacasereport AT asemshadid bullouslichenplanustreatedwithadalimumabacasereport |