Fusion of glioma-associated mesenchymal stem/stromal cells with glioma cells promotes macrophage recruitment and M2 polarization via m6A modification of CSF1

Fusion of glioma-associated mesenchymal stem/stromal cells with glioma cells promotes macrophage recruitment and M2 polarization via m6A modification of CSF1

Abstract Malignant glioma is the most common primary malignant tumor of the brain in adults, with glioblastoma (GBM) being the most aggressive subtype. Mesenchymal stem/stromal cells (MSCs) have been shown to fuse with tumor cells in various cancers including glioma, thereby regulating tumor progres...

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Main Authors: Zhen Liu, Sujie Gu, Zesheng Peng, Yihao Wang, Hui Li, Xiaoqing Zeng, Haofei Wang, Peng Lv, Yuyi Wu, Yan Zhou, Yanbin Zhang, Xiaobing Jiang, Peng Fu
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07678-x
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