Melioidosis with Septic Shock and Disseminated Infection in a Neutropenic Patient Receiving Chemotherapy

Melioidosis is a bacterial infection, caused by Gram-negative bacillus, Burkholderia pseudomallei, widespread in Southeast Asia and the northern part of Australia, resulting in a high mortality rate in severe infection. However, it has rarely been reported in patients with chemotherapy-induced neutr...

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Main Authors: Sitthi Sukauichai, Chantana Pattarowas
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2020/8976180
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author Sitthi Sukauichai
Chantana Pattarowas
author_facet Sitthi Sukauichai
Chantana Pattarowas
author_sort Sitthi Sukauichai
collection DOAJ
description Melioidosis is a bacterial infection, caused by Gram-negative bacillus, Burkholderia pseudomallei, widespread in Southeast Asia and the northern part of Australia, resulting in a high mortality rate in severe infection. However, it has rarely been reported in patients with chemotherapy-induced neutropenia. The authors described a case of melioidosis in a neutropenic patient presenting with septic shock after receiving chemotherapy. Blood and urine cultures were positive for Burkholderia pseudomallei, and CT scan showed multiple pulmonary nodules and hepatosplenic abscesses. The patient was successfully treated with antibiotics for the infection and with combined modalities for a malignancy.
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institution Kabale University
issn 2090-6625
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series Case Reports in Infectious Diseases
spelling doaj-art-a63aee68ad4a49a78f3c879cf17c91b42025-08-20T03:38:44ZengWileyCase Reports in Infectious Diseases2090-66252090-66332020-01-01202010.1155/2020/89761808976180Melioidosis with Septic Shock and Disseminated Infection in a Neutropenic Patient Receiving ChemotherapySitthi Sukauichai0Chantana Pattarowas1Chonburi Cancer Hospital, Department of Chemotherapy, Chonburi, ThailandChonburi Cancer Hospital, Department of Radiology, Chonburi, ThailandMelioidosis is a bacterial infection, caused by Gram-negative bacillus, Burkholderia pseudomallei, widespread in Southeast Asia and the northern part of Australia, resulting in a high mortality rate in severe infection. However, it has rarely been reported in patients with chemotherapy-induced neutropenia. The authors described a case of melioidosis in a neutropenic patient presenting with septic shock after receiving chemotherapy. Blood and urine cultures were positive for Burkholderia pseudomallei, and CT scan showed multiple pulmonary nodules and hepatosplenic abscesses. The patient was successfully treated with antibiotics for the infection and with combined modalities for a malignancy.http://dx.doi.org/10.1155/2020/8976180
spellingShingle Sitthi Sukauichai
Chantana Pattarowas
Melioidosis with Septic Shock and Disseminated Infection in a Neutropenic Patient Receiving Chemotherapy
Case Reports in Infectious Diseases
title Melioidosis with Septic Shock and Disseminated Infection in a Neutropenic Patient Receiving Chemotherapy
title_full Melioidosis with Septic Shock and Disseminated Infection in a Neutropenic Patient Receiving Chemotherapy
title_fullStr Melioidosis with Septic Shock and Disseminated Infection in a Neutropenic Patient Receiving Chemotherapy
title_full_unstemmed Melioidosis with Septic Shock and Disseminated Infection in a Neutropenic Patient Receiving Chemotherapy
title_short Melioidosis with Septic Shock and Disseminated Infection in a Neutropenic Patient Receiving Chemotherapy
title_sort melioidosis with septic shock and disseminated infection in a neutropenic patient receiving chemotherapy
url http://dx.doi.org/10.1155/2020/8976180
work_keys_str_mv AT sitthisukauichai melioidosiswithsepticshockanddisseminatedinfectioninaneutropenicpatientreceivingchemotherapy
AT chantanapattarowas melioidosiswithsepticshockanddisseminatedinfectioninaneutropenicpatientreceivingchemotherapy